Screening

Informed consent, decisional capacity, autonomy, and withdrawal rights

Teaches how to obtain and maintain valid informed consent through clear disclosure, comprehension checks, capacity support, voluntariness, non-coercion, and respect for refusal or withdrawal. The competency also covers consent for screening procedures, recordings, collateral contact, rescue interventions, and documentation of the consent process.

4 roles · 59 guidelines · 0 courses · 0 providers

Confidentiality, privacy, and research data protection

Teaches protection of participant identity, sensitive clinical or occupational information, recordings, and research data. The competency covers coded identifiers, restricted access, secure handling, confidentiality safeguards, and privacy-preserving documentation.

5 roles · 53 guidelines · 0 courses · 0 providers

Screening, eligibility, and readiness assessment

Teaches how to assess clinical suitability before psychedelic or ketamine treatment, including medical and psychiatric screening, readiness evaluation, contraindication review, inclusion/exclusion criteria, and ongoing eligibility re-checks before dosing.

8 roles · 52 guidelines · 15 courses · 12 providers

Acute psychological response and emergency management during dosing

Cluster covering 35 related competencies for monitoring acute psychological effects, recognising and managing distress, crisis containment, emergency escalation, and rescue-medication coordination during psychedelic dosing sessions.

6 roles · 51 guidelines · 2 courses · 2 providers

Adverse event identification, documentation, and reporting

Teaches how to detect, elicit, document, and report adverse events and serious adverse events across the participant journey. The focus is accurate source documentation, regulatory reporting discipline, follow-up, and preservation of participant safety and trial integrity.

4 roles · 46 guidelines · 0 courses · 0 providers

Preparation and integration support

Cluster covering 31 related competencies including: Integration support, Integration therapy, Integration coaching.

7 roles · 43 guidelines · 18 courses · 14 providers

Suicide and serious psychiatric risk assessment

Teaches structured assessment of suicidal ideation, intent, psychiatric deterioration, and related high-risk presentations. Learners are trained to use appropriate tools, safety planning, emergency contacts, clinician access, and escalation pathways when risk is identified.

6 roles · 41 guidelines · 1 courses · 1 providers

Manual fidelity, protocol adherence, and deviation management

Teaches faithful delivery of manualized treatment and protocol-defined procedures while documenting and managing unavoidable deviations. The competency protects participant welfare, treatment consistency, data integrity, and sponsor oversight.

5 roles · 39 guidelines · 0 courses · 0 providers

Post-dose follow-up, safety monitoring, and retention support

Teaches ongoing participant contact after dosing to support stability, detect delayed adverse effects, maintain therapeutic containment, and sustain adherence to follow-up visits and outcome assessments.

5 roles · 37 guidelines · 0 courses · 0 providers

Discharge readiness, escort safety, and post-session supervision

Teaches how to determine when a participant is safe to leave after dosing and how to arrange appropriate supervision afterward. The competency covers psychological and physical stability, escort/support-person coordination, discharge restrictions, overnight or post-session support, and follow-up contact when needed.

4 roles · 30 guidelines · 0 courses · 0 providers

Emergency recognition, escalation, and disposition planning

Teaches recognition of medical or psychiatric emergencies and the steps required to escalate care safely. The competency includes de-escalation, clinical consultation, 911 or emergency department transfer, serious-event escalation, and referral to appropriate higher-level care.

7 roles · 29 guidelines · 3 courses · 3 providers

Blinding, allocation concealment, and unblinding control

Teaches how to preserve blinded trial conduct across participant interactions, outcome collection, staff roles, and session procedures. The competency includes preventing accidental unblinding, minimizing bias, and using emergency unblinding only when clinically necessary.

6 roles · 29 guidelines · 0 courses · 0 providers

Medication, substance-use, washout, and taper management

Teaches review and management of concomitant medications, restricted therapies, prohibited substances, washout periods, tapering requirements, and abstinence expectations. The competency includes participant counseling, medication reconciliation, sponsor notification, and team coordination when restrictions affect safety or interpretability.

5 roles · 29 guidelines · 0 courses · 0 providers

Study documentation, data integrity, and regulatory recordkeeping

Teaches accurate study documentation, source-record quality, secure data capture, Good Clinical Practice recordkeeping, IRB and sponsor documentation requirements, monitoring readiness, audit support, accountability, and retention obligations.

3 roles · 27 guidelines · 0 courses · 0 providers

Manualized psychedelic psychotherapy delivery

Teaches delivery of psychedelic-assisted psychotherapy according to an approved study manual across preparation, dosing, integration, and follow-up. The competency balances standardized structure with non-directive support for the participant’s therapeutic process.

4 roles · 25 guidelines · 3 courses · 2 providers

Therapeutic boundaries, professional conduct, and consent for touch

Teaches how to maintain clear relational and physical boundaries in emotionally vulnerable treatment settings. This includes professional conduct, rapport without overreach, explicit consent for touch, the right to revoke consent, and strict prohibition of sexual or erotic contact.

7 roles · 24 guidelines · 4 courses · 3 providers

Co-therapist and multidisciplinary team coordination

Teaches coordinated practice across co-therapists, physicians, psychiatrists, study coordinators, principal investigators, and other care-team members. The focus is shared responsibility, clear communication, role clarity, and coordinated observation of participant status.

4 roles · 24 guidelines · 0 courses · 0 providers

Study record and trial registration literacy

Teaches how to understand ClinicalTrials.gov records and related study information, including glossary terms, registration fields, protocol descriptors, and results-reporting elements used to interpret clinical research records.

3 roles · 24 guidelines · 0 courses · 0 providers

Physical safety monitoring

Cluster covering 3 related competencies including: Physical safety monitoring, Safety monitoring during dosing sessions, Medical safety monitoring during psilocybin administration.

5 roles · 19 guidelines · 0 courses · 0 providers

Acute psychiatric and behavioral risk monitoring

Teaches continuous monitoring for distress, confusion, psychotic symptoms, suicidality, agitation, and other acute behavioral risks during and after dosing. The focus is early recognition, documentation, and escalation to clinical support when risk emerges.

5 roles · 17 guidelines · 0 courses · 0 providers

Preparation support

Cluster covering 11 related competencies including: Preparation support, Psilocybin preparation, Therapeutic preparation.

3 roles · 16 guidelines · 6 courses · 5 providers

Ethical conduct in human-subject research

Able to practice ethically in a clinical trial environment involving a Schedule-sensitive psychoactive intervention. This includes protecting participants, adhering to protocol, and supporting valid informed participation.

3 roles · 16 guidelines · 0 courses · 0 providers

Supportive nondirective therapeutic stance

Cluster covering 6 related competencies including: Therapeutic support during dosing, Nondirective dosing-session presence, Supportive dosing-session facilitation.

2 roles · 16 guidelines · 0 courses · 0 providers

Therapeutic alliance building

Cluster covering 2 related competencies including: Therapeutic alliance building, Therapeutic alliance and rapport building.

2 roles · 15 guidelines · 1 courses · 1 providers

Good Clinical Practice and protocol procedure compliance

Teaches adherence to Good Clinical Practice, assigned study roles, protocol procedures, delegation boundaries, and applicable research regulations. The competency supports consistent execution of approved procedures across sites and participants.

4 roles · 15 guidelines · 0 courses · 0 providers

Psilocybin session facilitation

Cluster covering 9 related competencies including: Psilocybin facilitation, Psilocybin session support, Psilocybin facilitation basics.

6 roles · 14 guidelines · 6 courses · 5 providers

Adverse effects and side-effect management

Teaches recognition and management of expected and unexpected side effects during psychedelic or ketamine treatment. The competency emphasizes active observation, supportive response, and clinical escalation when symptoms exceed routine tolerability.

6 roles · 14 guidelines · 1 courses · 1 providers

Psychedelic-assisted psychotherapy preparation and integration

Teaches structured pre-dose preparation and post-dose integration as the therapeutic frame for psychedelic-assisted psychotherapy. The therapist supports rapport, intention clarification, meaning-making, emotional processing, and consolidation of insights after dosing.

6 roles · 13 guidelines · 2 courses · 2 providers

Hallucinogen pharmacology and effects

Cluster covering 7 related competencies including: Physiologic safety awareness, Hallucinogen pharmacology and effects, Hallucinogen-assisted therapy knowledge.

4 roles · 13 guidelines · 0 courses · 0 providers

Ketamine psychotherapy delivery

Cluster covering 12 related competencies including: KAP psychotherapy delivery, Ketamine and KAP knowledge, Ketamine integration planning.

6 roles · 12 guidelines · 7 courses · 5 providers

Dissociation and acute neuropsychiatric effect monitoring

Teaches recognition and documentation of dissociation, psychosis-like symptoms, mania, and other acute neuropsychiatric effects that can occur after ketamine, psychedelic dosing, or related interventions. The focus is monitoring, reporting, and escalation when symptoms become clinically significant.

5 roles · 12 guidelines · 0 courses · 0 providers

Physiologic monitoring, thermoregulation, hydration, and overdose response

Teaches monitoring and response for acute physiological risks, including vital signs, temperature, hydration, overheating, excessive fluid intake, and suspected overdose. The competency emphasizes supportive care, medical coordination, documentation, and escalation when needed.

6 roles · 11 guidelines · 0 courses · 0 providers

Special-interest adverse event vigilance

The protocol requires active monitoring for psychedelic-specific adverse events such as hallucinations, psychotic symptoms, dissociation, mood alteration, and cognitive disturbance. These require immediate notification and follow-up.

3 roles · 11 guidelines · 0 courses · 0 providers

Depression symptom and remission monitoring

Teaches structured monitoring of depressive symptoms, response, and remission across treatment and follow-up. Learners use standardized scales and clinical review to track change and identify deterioration or non-response.

2 roles · 10 guidelines · 0 courses · 0 providers

Comprehensive psychiatric assessment

Ability to perform or supervise detailed psychiatric evaluation for diagnosis, eligibility, and ongoing monitoring. The therapist/facilitator must understand symptom presentations relevant to MDD, AUD, suicidality, psychosis, and dissociation.

3 roles · 9 guidelines · 0 courses · 0 providers

Ensure confidentiality and session containment

Maintain a contained therapeutic environment that protects the patient’s privacy and minimizes unwanted exposure. The session structure emphasizes confidentiality and controlled access to stimulation and outside contact.

2 roles · 9 guidelines · 0 courses · 0 providers

Outcome Measure and Assessment Literacy

Teaches clinicians and research staff to understand the purpose, limits, scoring, interpretation, and clinical meaning of psychological measures and study instruments used to evaluate symptoms, functioning, safety, and treatment outcomes.

3 roles · 9 guidelines · 0 courses · 0 providers

Client preparation and therapeutic set/setting

Cluster covering 2 related competencies including: Preparation of set and setting, Client preparation and therapeutic set/setting.

3 roles · 8 guidelines · 2 courses · 2 providers

Continuation, discontinuation, and risk-benefit judgment

Teaches how clinicians determine whether a participant should proceed, pause, discontinue dosing, or terminate study participation. The competency centers on safety-driven clinical judgment, risk-benefit assessment, and early termination when continuation is no longer appropriate.

5 roles · 8 guidelines · 0 courses · 0 providers

Participant safety restriction counseling

Teaches how to instruct participants on post-dose and study-period restrictions that reduce risk from impaired judgment, unsafe activity, prohibited substances, or behaviors that could confound study outcomes.

3 roles · 8 guidelines · 0 courses · 0 providers

Physiologic monitoring during ketamine administration

Cluster covering 2 related competencies including: Safety monitoring during ketamine dosing, Physiologic monitoring during ketamine administration.

4 roles · 8 guidelines · 0 courses · 0 providers

Use outcome assessment and follow-up to evaluate response

The study used standardized anxiety measures and followed patients for 2 months and 12 months, implying competence in tracking outcomes over time. Therapists should be able to assess symptom change and sustained benefit using structured follow-up.

2 roles · 8 guidelines · 0 courses · 0 providers

Vital sign and physical distress monitoring

Monitors participant physical status during study visits and identifies concerning changes requiring escalation. Vital signs and symptomatic changes are part of routine safety observation.

4 roles · 8 guidelines · 0 courses · 0 providers

Cultural humility, Indigenous respect, and equity-oriented care

Teaches culturally responsive psychedelic care, including humility, anti-bias practice, Indigenous and traditional-use awareness, cultural appropriation concerns, diversity and inclusion, and respectful work with marginalized communities.

6 roles · 7 guidelines · 11 courses · 10 providers

Clinical interviewing and history-taking

Therapists and study clinicians perform detailed biopsychosocial interviewing during preparation and screening. This supports treatment planning, risk assessment, and therapeutic understanding.

2 roles · 7 guidelines · 0 courses · 0 providers

Clinical Interviewing and PTSD Assessment

Teaches structured clinical interviewing and assessment administration for PTSD and related symptom domains, including symptom severity, functional impairment, risk factors, and appropriate use of standardized assessment tools.

2 roles · 7 guidelines · 0 courses · 0 providers

Participant-centered discharge planning and aftercare

Support decision-making about ongoing treatment after trial completion, particularly for participants who received escitalopram. The clinician helps participants consider whether to continue, taper, or return to usual care.

3 roles · 7 guidelines · 0 courses · 0 providers

Integration and post-session debriefing

Cluster covering 4 related competencies including: Integration and debriefing, Integration and debriefing facilitation, Integration and post-session debriefing.

2 roles · 6 guidelines · 0 courses · 0 providers

Ketamine infusion monitoring

Cluster covering 5 related competencies including: Cardiac safety monitoring, Ketamine infusion monitoring, Ketamine infusion administration.

3 roles · 6 guidelines · 0 courses · 0 providers

Medical screening and medication review

Therapists/investigators must understand the medical suitability requirements for LSD-assisted psychotherapy and coordinate medication washout and concomitant medication review. This includes recognizing drug-drug interaction risks and contraindications.

3 roles · 6 guidelines · 0 courses · 0 providers

Medication taper and withdrawal monitoring

Teaches monitoring during down-titration or discontinuation of psychiatric medications before dosing. Learners track withdrawal symptoms, symptom worsening, suicidality, and other risks that may emerge during tapering.

4 roles · 6 guidelines · 0 courses · 0 providers

Professional boundaries and recording consent

Therapists may record sessions only with explicit participant consent and must handle recordings for training and research within protocol limits. Recording is part of the therapeutic and scientific framework, not routine clinical use.

3 roles · 6 guidelines · 0 courses · 0 providers

Reproductive risk, contraception, and pregnancy monitoring

Teaches counseling and monitoring around contraception, reproductive restrictions, pregnancy risk, and pregnancy-related discontinuation rules. Learners are trained to explain requirements clearly and respond promptly when pregnancy or reproductive-safety concerns arise.

2 roles · 6 guidelines · 0 courses · 0 providers

Safe treatment-setting facilitation

Provide a calm and supportive environment during treatment to reduce distress and support tolerance of the experience. The case report notes food, rest, and a quiet place as part of care.

2 roles · 6 guidelines · 0 courses · 0 providers

Psilocybin psychotherapy framework

Cluster covering 4 related competencies including: Psychedelic therapy workflow, Psilocybin psychotherapy framework, Psilocybin-assisted psychotherapy framework.

6 roles · 5 guidelines · 4 courses · 2 providers

Ethical psychedelic facilitation

Cluster covering 3 related competencies including: Ethical psychedelic facilitation, Safe, legal psychedelic care facilitation, Ethical decision-making in psychedelic facilitation.

7 roles · 5 guidelines · 2 courses · 2 providers

Management of concomitant medication interactions

Cluster covering 5 related competencies including: Concomitant medication review, Contraindication and interaction awareness, Contraindications, drug effects, and interactions.

4 roles · 5 guidelines · 1 courses · 1 providers

Assessment administration and interpretation

Ability to administer and interpret structured interviews, clinician ratings, and self-report measures used in the study. Therapists contribute to eligibility, safety, and outcome assessment.

2 roles · 5 guidelines · 0 courses · 0 providers

Evaluate clinically significant response and treatment outcomes

Therapists/facilitators should be able to judge whether therapeutic change reaches clinically meaningful thresholds, not just whether symptoms improve numerically. This supports informed ongoing care and communication about benefits and limitations.

2 roles · 5 guidelines · 0 courses · 0 providers

Knowledge of PTSD and fear extinction theory

Understand the clinical and neurobehavioral rationale for PE and exposure-based treatment. The therapist should know how extinction learning is conceptualized in the study model.

2 roles · 5 guidelines · 0 courses · 0 providers

Participant education and informed consent communication

Clinicians and research staff must clearly educate participants about study procedures, risks, side effects, restrictions, and possible benefits, and obtain written informed consent before screening and study participation. Ethical delivery depends on transparent communication and opportunities for questions.

2 roles · 5 guidelines · 0 courses · 0 providers

Research assessment administration

Administer study measures and structured assessments on schedule, including psychological, spiritual, and neurobehavioral instruments. This includes both paper-based and Storyline-based assessments.

2 roles · 5 guidelines · 0 courses · 0 providers

Risk screening and exclusion judgment

Know the medical and psychiatric exclusions that protect participants from foreseeable harm. Facilitators must recognize conditions that make MDMA-assisted psychotherapy unsafe or inappropriate.

3 roles · 5 guidelines · 0 courses · 0 providers

Understand dose-response and time course

The facilitator should know how oral and intravenous dosing relate to onset, duration, and peak effects. This knowledge supports proper session planning, monitoring, and integration timing.

2 roles · 5 guidelines · 0 courses · 0 providers

Risk evaluation and safety monitoring

Teaches continuous evaluation of clinical risk and maintenance of a safe care environment throughout preparation, dosing, and follow-up. Learners monitor risk signals, apply safety procedures, and escalate care when needed.

6 roles · 4 guidelines · 3 courses · 2 providers

Therapeutic touch judgment

The training includes appropriate use of therapeutic touch as part of safe delivery. Learners are expected to use touch judiciously and within ethical boundaries.

4 roles · 4 guidelines · 1 courses · 1 providers

Addiction and OUD treatment knowledge

Facilitator must understand opioid use disorder, medication-assisted treatment, and the clinical rationale for adjunctive psychotherapy. The protocol frames MORE+KAP as an investigational augmentation to buprenorphine treatment.

2 roles · 4 guidelines · 0 courses · 0 providers

Independent outcome assessment administration

The facilitator must administer and coordinate patient-rated and clinician-rated measures while minimizing bias. Assessments should be completed independently and in the correct order.

3 roles · 4 guidelines · 0 courses · 0 providers

Monitor acute and short-term adverse effects

The study emphasizes the absence of acute or chronic adverse effects persisting beyond 1 day and no treatment-related serious adverse events, indicating the need for active monitoring during and after treatment. Facilitators must be able to observe, document, and respond to adverse reactions.

2 roles · 4 guidelines · 0 courses · 0 providers

Pre-session dosing behavior instructions

Teaches clear communication of behavioral requirements before dosing sessions so conditions are standardized and preventable risks are reduced. Staff confirm that participants understand and follow pre-session instructions.

3 roles · 4 guidelines · 0 courses · 0 providers

Prioritize participant wellbeing over research aims

Participant safety and wellbeing must take precedence over scientific objectives at all times. Therapists must communicate and operationalize this priority throughout screening, treatment, and follow-up.

3 roles · 4 guidelines · 0 courses · 0 providers

Recognition of contraindications and risk states

Therapists/facilitators must know the psychiatric and medical conditions that make KPT unsafe or inappropriate. Safe practice depends on excluding high-risk individuals.

2 roles · 4 guidelines · 0 courses · 0 providers

Recognize limits of evidence and avoid overstatement

Therapists and facilitators should communicate treatment effects responsibly and acknowledge methodological limitations. The paper notes small sample size, lack of long-term control group, and need for further study of mechanisms.

2 roles · 4 guidelines · 0 courses · 0 providers

Structured symptom rating administration

Facilitators must competently administer and interpret clinician-rated ADHD and global severity measures. Accurate scoring is essential because these scales determine eligibility and outcomes.

3 roles · 4 guidelines · 0 courses · 0 providers

Substance use assessment

Ability to evaluate alcohol and other substance use patterns using standardized tools and clinical interview. This is essential for eligibility, safety, and outcome monitoring.

2 roles · 4 guidelines · 0 courses · 0 providers

Crisis and adverse-event response

The page signals training in managing difficult or high-risk moments, including crisis intervention and trigger management. Learners are expected to respond appropriately when a session becomes destabilizing or unsafe.

6 roles · 3 guidelines · 1 courses · 1 providers

Safety monitoring and emergency awareness

The page points to checklists and a guide to basic medical emergencies, indicating that learners should be able to monitor safety and recognize urgent issues. The overall training context also stresses keeping both client and practitioner safe.

5 roles · 3 guidelines · 1 courses · 1 providers

Behavioral monitoring and outcome assessment

Collect smoking-related behavioral data and participant-reported outcomes repeatedly across the trial. Facilitators must accurately gather self-report, breath CO, urine, and questionnaire data according to protocol.

3 roles · 3 guidelines · 0 courses · 0 providers

Blinded Assessment and Independent Rating

Teaches the use of independent or blinded assessors to reduce expectancy and observer bias, preserve separation between therapeutic and rating roles, manage unblinding risks, and protect outcome validity in open-label or partially blinded designs.

3 roles · 3 guidelines · 0 courses · 0 providers

Cardiac risk monitoring

Monitor for ibogaine-associated cardiac toxicity, especially QTc prolongation and risk of torsades de pointes. This includes baseline exclusion screening, frequent ECG surveillance, and escalation when QTc becomes markedly prolonged.

2 roles · 3 guidelines · 0 courses · 0 providers

Knowledge of MDMA effects and risks

Facilitators must understand the expected psychological, physiological, and potential adverse effects of MDMA in order to prepare participants, support the session, and detect complications.

3 roles · 3 guidelines · 0 courses · 0 providers

Laboratory and ECG safety review

Reviews laboratory and ECG data for clinically relevant abnormalities and determines whether continued participation is appropriate. Escalates abnormalities requiring repeat testing or specialist input.

2 roles · 3 guidelines · 0 courses · 0 providers

MRI safety screening and imaging-session coordination

Teaches screening for MRI contraindications and coordination of imaging clearance before scan procedures. The competency prevents exposure of ineligible participants to magnetic-resonance risks and supports safe imaging-session logistics.

3 roles · 3 guidelines · 0 courses · 0 providers

Opioid withdrawal assessment

Evaluates opioid withdrawal symptoms and tracks changes over time in participants discontinuing methadone OST. Uses standardized withdrawal ratings to assess potential treatment effects and safety.

2 roles · 3 guidelines · 0 courses · 0 providers

Pre-treatment clinical risk assessment

Understand the major medical risks associated with ibogaine administration, especially cardiac and neurologic toxicity, before proceeding with treatment. This includes recognizing that ibogaine has been linked to torsades de pointes, QTc prolongation, bradycardia, and ataxia.

3 roles · 3 guidelines · 0 courses · 0 providers

Professional qualifications and experience threshold

The manual specifies baseline professional requirements for study therapists. These include licensure and substantial clinical experience with psychiatric populations.

3 roles · 3 guidelines · 0 courses · 0 providers

Psychological state assessment

Administer and interpret psychological and psychometric measures relevant to mood, cravings, expectations, mystical experience, ego dissolution, and functioning. Facilitators must accurately support questionnaire-based assessment across time points.

2 roles · 3 guidelines · 0 courses · 0 providers

Research rating fidelity

Ability to administer standardized clinical ratings consistently and under supervision. Reliable measurement is essential for efficacy and safety endpoints.

4 roles · 3 guidelines · 0 courses · 0 providers

Safety monitoring of vital signs and cardiovascular effects

Monitor and respond to the expected sympathomimetic effects of MDMA. The therapist/facilitator must be alert to transient increases in blood pressure, pulse, and related cardiac symptoms.

2 roles · 3 guidelines · 0 courses · 0 providers

Substance use relapse monitoring

Ability to monitor for opioid use recurrence, other substance use, and ketamine misuse during the trial. The clinician must recognize relapse risk and take action when substance use worsens.

2 roles · 3 guidelines · 0 courses · 0 providers

Support safe administration of LSD dosing sessions

Because the protocol involved specific LSD doses, active placebo control, and session spacing, facilitators need applied skill in implementing dosing-session procedures safely and consistently. This includes maintaining therapeutic support while adhering to protocol constraints.

2 roles · 3 guidelines · 0 courses · 0 providers

Support structured symptom monitoring

Although formal measurements may be conducted by another researcher, therapists/facilitators must work within a protocol that includes repeated anxiety assessments and daily diaries of anxiety, pain, and medication use. This implies competence in reinforcing adherence to monitoring procedures and integrating findings into care awareness.

2 roles · 3 guidelines · 0 courses · 0 providers

Training and certification in study instruments

Teaches the requirement for site personnel to be trained and certified on protocol-specific assessments, psychiatric instruments, rating scales, and study procedures before performing them in the trial.

3 roles · 3 guidelines · 0 courses · 0 providers

TRD eligibility assessment

Understands and applies the protocol-defined criteria for treatment-resistant major depressive disorder, including diagnostic confirmation, episode severity, and prior treatment failure requirements. Must verify both current and historical antidepressant nonresponse and ensure the participant remains eligible at baseline.

2 roles · 3 guidelines · 0 courses · 0 providers

Understanding of trial procedures and schedule

Know the sequence, timing, and purpose of screening, preparation, dosing, scanning, follow-up, and unblinding visits. The therapist/facilitator must be able to work within the full protocol structure.

2 roles · 3 guidelines · 0 courses · 0 providers

Virtual care facilitation

Capacity to conduct assessments and therapy sessions virtually when needed while preserving safety and confidentiality. The study permits telehealth sessions for certain visits and contingencies.

2 roles · 3 guidelines · 0 courses · 0 providers

Voluntary participation and non-coercion

The handbook explicitly states that the experience should be fully explained and that the subject should accept it voluntarily. Coercion is framed as both unethical and therapeutically counterproductive.

2 roles · 3 guidelines · 0 courses · 0 providers

Harm reduction and risk awareness

Cluster covering 5 related competencies including: Harm-reduction orientation, Harm reduction and risk awareness, Harm reduction for client support.

7 roles · 2 guidelines · 5 courses · 5 providers

Legal and Regulatory Navigation

Teaches practitioners to identify and apply relevant legal, regulatory, ethical, and institutional requirements, including documentation, consent, reporting, controlled-substance, and jurisdiction-specific obligations.

6 roles · 2 guidelines · 2 courses · 2 providers

Assess and engage support systems

Therapists should understand the participant’s support network and appropriately involve support persons when relevant and desired.

2 roles · 2 guidelines · 0 courses · 0 providers

Assessment of emotional stability after sessions

Therapists must remain with participants at the end of and immediately after experimental sessions until emotional stability is established. This requires real-time clinical judgment about readiness for reduced supervision.

4 roles · 2 guidelines · 0 courses · 0 providers

Assessment of indications and contraindications

The therapist must exercise clinical judgment about who may benefit, who may have difficulty surrendering defenses, and where evidence is limited. The handbook emphasizes uncertainty, need for research, and cautious selection based on insecurity, rigidity, suspicion, diagnosis, and treatment goals.

2 roles · 2 guidelines · 0 courses · 0 providers

Assessment-driven therapeutic tailoring

Uses assessment findings to individualize therapy and medication-session preparation. Adapts the approach based on participant response, goals, and clinical presentation.

1 role · 2 guidelines · 0 courses · 0 providers

Baseline history taking

Collect and interpret baseline behavioral, psychiatric, and medical history relevant to psilocybin research. This information is used to determine eligibility and contextualize outcomes.

2 roles · 2 guidelines · 0 courses · 0 providers

Clinical trial participant eligibility boundaries

Therapists must practice within the population and setting defined by the manual, limiting use to approved clinical trial subjects with PTSD. This boundary helps protect participants and preserves research integrity.

2 roles · 2 guidelines · 0 courses · 0 providers

Cognitive safety monitoring

Ability to monitor for short-term cognitive impairment following psychedelic administration. The study included tests designed to detect decrements in attention and processing speed.

2 roles · 2 guidelines · 0 courses · 0 providers

Competence in protocol adherence for dosing sessions

The intervention involved two separate psilocybin dosing sessions 3 weeks apart under a randomized controlled protocol, implying the need for facilitators to reliably support treatment according to a fixed schedule and study procedures.

2 roles · 2 guidelines · 0 courses · 0 providers

Coordinate with outside providers ethically

Therapists must coordinate with prescribing clinicians and existing psychotherapists when relevant, while respecting consent and confidentiality. Communication should support safety, continuity, and protocol integrity.

4 roles · 2 guidelines · 0 courses · 0 providers

Empathic presence and active listening

Therapists are expected to provide consistent empathic presence, nonjudgmental attunement, and deep listening throughout the process. This includes validating feelings, listening for deeper meaning, and creating psychological permission for openness.

2 roles · 2 guidelines · 0 courses · 0 providers

Laboratory safety monitoring

Review laboratory and biomarker data for clinically significant abnormalities, including chemistry, hematology, coagulation, and alcohol biomarkers. This supports medical safety surveillance during follow-up.

2 roles · 2 guidelines · 0 courses · 0 providers

Management of assessment-related distress

Because interviews and questionnaires may provoke emotional reactions or fatigue, facilitators must respond supportively and mitigate burden. This includes addressing distress during assessments and offering breaks.

2 roles · 2 guidelines · 0 courses · 0 providers

Monitor broad domains of well-being beyond symptom reduction

Safety monitoring in this context includes tracking not only adverse psychiatric states but also broader psychological, emotional, existential, and spiritual outcomes. Clinicians should watch for changes across multiple domains that may affect patient functioning and care needs.

1 role · 2 guidelines · 0 courses · 0 providers

Motivational interviewing and enhancement

Uses motivational interviewing methods to strengthen intrinsic motivation and commitment to change. Tailors discussions to the participant’s ambivalence, goals, and readiness to change drinking behavior.

2 roles · 2 guidelines · 0 courses · 0 providers

Nasal tolerability assessment

Performs targeted nasal examinations and assesses local tolerability of esketamine nasal spray. Identifies findings that could affect drug delivery, safety, or continuation.

2 roles · 2 guidelines · 0 courses · 0 providers

Neutral, unbiased facilitation

The facilitator must minimize bias in how assessments are administered and in how participant responses are handled. This is important because the trial is open-label and relies heavily on patient-reported outcomes.

2 roles · 2 guidelines · 0 courses · 0 providers

Non-responder handoff and continuity of care

The facilitator must ensure non-responders are transitioned safely back to clinical care. Continuity of care is explicitly required to support ongoing psychiatric treatment.

2 roles · 2 guidelines · 0 courses · 0 providers

Optional biomarker/genomic research handling

Understands the optional nature and operational limits of biomarker and pharmacogenomic collection. Ensures consent, timing, fasting guidance, and sample handling requirements are respected.

2 roles · 2 guidelines · 0 courses · 0 providers

Outcome and safety measure literacy

Knowledge of the trial’s primary, secondary, and exploratory endpoints and the instruments used to assess them. This enables accurate administration and interpretation of study procedures.

2 roles · 2 guidelines · 0 courses · 0 providers

Peak experience assessment

Ability to assess whether the target acute psychedelic experience has occurred using the study-defined scale and threshold. This was used to guide individualized dosing.

2 roles · 2 guidelines · 0 courses · 0 providers

Professional licensure and supervision

Therapists must meet licensure requirements and work within supervision structures appropriate to their training and role. Unlicensed or PAP-inexperienced staff require direct supervision.

2 roles · 2 guidelines · 0 courses · 0 providers

Protection against coercion and dual-role influence

The protocol explicitly addresses the risk of undue influence when investigators recruit current or former patients, requiring safeguards and ongoing monitoring for coercion.

2 roles · 2 guidelines · 0 courses · 0 providers

Protocol adherence and visit scheduling

Ability to manage the study schedule, windows, and follow-up procedures accurately. This supports treatment delivery and valid outcome collection.

2 roles · 2 guidelines · 0 courses · 0 providers

Psychedelic phenomenology literacy

Understand the characteristic acute experiential domains elicited by ayahuasca. This includes perceptual, somatic, cognitive, affective, mystical, and temporal-spatial alterations.

2 roles · 2 guidelines · 0 courses · 0 providers

Respiratory monitoring

Facilitators must watch for slowed breathing, sleep apnea-related hypoxia, disordered breathing, and oxygen desaturation. Oxygenation needs ongoing assessment during the acute and post-acute periods.

2 roles · 2 guidelines · 0 courses · 0 providers

Retention and engagement skills

Given the risk of high attrition, facilitators need strong engagement and follow-up skills. The protocol explicitly notes the importance of respecting time commitments, tracking procedures, and strong interpersonal skills of study personnel.

1 role · 2 guidelines · 0 courses · 0 providers

Shared decision-making and referral coordination

Collaborates with patients, medical practitioners, and referring providers to support individualized care. Helps patients consider alternatives and coordinate ongoing treatment needs.

3 roles · 2 guidelines · 0 courses · 0 providers

Track cognitive performance during treatment

Because cognitive performance during treatment is a named secondary outcome, clinicians involved in care should be able to monitor and document cognitive functioning relevant to treatment participation. This supports safety oversight and interpretation of treatment effects.

2 roles · 2 guidelines · 0 courses · 0 providers

Use of structured clinical and psychological measures

Therapists/facilitators should know the main assessment domains used in KPT research and clinical monitoring, including craving, depression, anxiety, anhedonia, addiction severity, and purpose in life. This knowledge supports case formulation and tracking change.

2 roles · 2 guidelines · 0 courses · 0 providers

Use of structured rating scales

The therapist/facilitator or designated rater must administer and interpret multiple structured clinical scales reliably. Training and separation of roles are required to preserve rating quality and blinding.

3 roles · 2 guidelines · 0 courses · 0 providers

Withdrawal symptom assessment

Measure opioid withdrawal severity using standardized instruments and interpret symptom severity over time. Facilitators must be able to collect both objective observation and patient-reported data.

2 roles · 2 guidelines · 0 courses · 0 providers

Working with family/collateral supports

The protocol expects involvement of relatives in follow-up, indicating a facilitator competency in engaging collateral supports. This helps verify outcomes and sustain recovery monitoring.

2 roles · 2 guidelines · 0 courses · 0 providers

Psychedelic research literacy and evidence appraisal

Teaches how to interpret the psychedelic clinical evidence base, compare strength of evidence across indications, understand mechanism theories, and critically appraise research claims. The competency supports evidence-informed practice rather than relying on general field narratives.

7 roles · 1 guidelines · 11 courses · 8 providers

Trauma-informed care

Cluster covering 2 related competencies including: Trauma-informed care, Trauma-informed psychedelic care.

4 roles · 1 guidelines · 4 courses · 4 providers

Professional Scope and Practice Alignment

Teaches clinicians to recognise their role boundaries, align services with training, licensure, supervision, and organisational policy, and refer or escalate when participant needs fall outside their scope of competence.

6 roles · 1 guidelines · 3 courses · 2 providers

Pharmacology, contraindications, and interaction awareness

Teaches psychoactive substance pharmacology, expected drug effects, contraindications, and relevant drug-interaction risks. The competency supports safer screening, medication review, participant education, and clinical decision-making.

6 roles · 1 guidelines · 2 courses · 2 providers

Confidentiality and trust maintenance

The course explicitly discusses confidentiality, especially in underground practice and with anonymous practitioners. Learners are expected to understand confidentiality as a core part of maintaining safe and effective psychedelic care relationships.

4 roles · 1 guidelines · 1 courses · 1 providers

Adaptation to diverse diagnoses

Ability to apply KAP flexibly across multiple diagnostic presentations. The article describes benefit in patients with a wide variety of diagnoses.

1 role · 1 guidelines · 0 courses · 0 providers

Alcohol abstinence screening and enforcement

Ensure required abstinence conditions are met before dosing and make clinical judgments about rescheduling or exclusion when they are not. This protects safety and protocol integrity.

2 roles · 1 guidelines · 0 courses · 0 providers

Alcohol use disorder assessment

Understands diagnostic and clinical features of alcohol dependence and related severity measures used in the protocol. Uses this knowledge to inform eligibility, treatment focus, and outcome interpretation.

2 roles · 1 guidelines · 0 courses · 0 providers

Alcohol withdrawal risk management

Clinicians must recognize the life-threatening nature of alcohol withdrawal and ensure adequate detoxification before treatment. Postponement and medical supervision are required when withdrawal risk is present.

1 role · 1 guidelines · 0 courses · 0 providers

Appropriate facilitator qualifications

Lead facilitators were doctoral-level psychologists or physicians with major depressive disorder treatment experience, and co-facilitators had at least a bachelor’s degree in a mental health-related field. The source therefore indicates role-appropriate clinical background and experience requirements.

2 roles · 1 guidelines · 0 courses · 0 providers

Assess psychosocial functioning

Competent delivery includes monitoring psychosocial functioning in addition to depressive symptoms. The source reports psychosocial functioning as a treatment outcome sustained through follow-up.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment administration and sequencing

Administer study assessments in the correct order and in the correct format. The protocol depends on reliable, standardized administration by trained site personnel and central raters.

1 role · 1 guidelines · 0 courses · 0 providers

Assessment fidelity and rater reliability

Demonstrate standardized rating competence and maintain reliable measurement over time. The protocol emphasizes training, calibration, and ongoing checks to prevent drift.

1 role · 1 guidelines · 0 courses · 0 providers

Assessment of existential distress and mood symptoms

Administer and interpret the study's psychosocial measures relevant to existential distress, depression, spiritual well-being, and death-related distress. These assessments are used for screening and outcome monitoring.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment of psychological readiness and vulnerability

Before administration, facilitators should assess readiness and factors that could increase the chance of a difficult session. The source highlights that preoccupation, rigidity, low trust, and poor support can worsen experiences.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment of treatment effectiveness

Ability to contribute to evaluation of the effectiveness of LSD-assisted psychotherapy. The study is explicitly described as investigating safety and effectiveness.

1 role · 1 guidelines · 0 courses · 0 providers

Assessment of treatment response

Track onset, duration, and phases of ibogaine effects as part of clinical monitoring. The manual describes multiple stages of effect and expects the provider to observe them carefully.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment-related participant support

Therapists and study staff must manage participant distress and fatigue associated with questionnaires and interviews. Competence includes pacing, offering breaks, and responding supportively to emotionally evocative content.

2 roles · 1 guidelines · 0 courses · 0 providers

Ataxia and neurologic monitoring

Assess for cerebellar adverse effects such as ataxia during and after ibogaine administration. The source indicates ataxia is likely driven by ibogaine exposure and should be tracked systematically.

2 roles · 1 guidelines · 0 courses · 0 providers

Attention to participant experience and perceived coercion

Therapists and research facilitators should evaluate how participants experienced study involvement, including perceived costs, benefits, and pressure to participate. This reflects an ethical responsibility to monitor the quality and voluntariness of participation over time.

2 roles · 1 guidelines · 0 courses · 0 providers

Awareness of interaction and formulation cautions

The therapist/facilitator must understand potential drug-interaction concerns and formulation-related differences that could alter tolerability or safety. The source mentions caution with antiemetics and alternative preparations.

2 roles · 1 guidelines · 0 courses · 0 providers

Ayahuasca pharmacology and dosing awareness

Facilitators need basic knowledge of ayahuasca composition, dosing, and interaction risks to support safe administration. The protocol emphasizes dose calculation, substance composition, and monitoring for contraindications.

1 role · 1 guidelines · 0 courses · 0 providers

Behavioral assessment administration

Trained staff must administer and/or supervise a battery of behavioral tasks and self-report instruments consistently across baseline and drug sessions. Some measures are verbally administered by clinicians or coordinators and require standardized delivery.

2 roles · 1 guidelines · 0 courses · 0 providers

Benzodiazepine-support management

Use supportive anxiolytic or hypnotic medication only when allowed and clinically indicated. This requires careful judgment to balance comfort, safety, and preservation of the session’s integrity.

2 roles · 1 guidelines · 0 courses · 0 providers

Boundary-setting around external supports and media

Therapists must help participants manage disclosure, social support, and media contact carefully to protect privacy and emotional safety. They should advise discretion without controlling the participant's choices.

1 role · 1 guidelines · 0 courses · 0 providers

Candidate selection and risk-benefit assessment

Evaluate whether a person is an appropriate candidate for ibogaine treatment by balancing potential benefit against medical risk. This includes identifying treatment-refractory opioid use disorder and weighing cardiotoxicity and other safety concerns against the harms of untreated substance use disorder.

2 roles · 1 guidelines · 0 courses · 0 providers

Cardiovascular safety screening

Screen for cardiovascular risk before treatment because ibogaine may prolong the QT interval and has been linked to arrhythmias and deaths. Exclude or carefully manage patients with cardiac disease and other risk factors.

2 roles · 1 guidelines · 0 courses · 0 providers

Causality assessment

Assess whether an event is related to treatment and resolve uncertainty through team discussion and regulatory escalation. The protocol uses a structured causality framework from unrelated to definitely related.

2 roles · 1 guidelines · 0 courses · 0 providers

Clinical judgment for exclusion of high-risk patients

Exclude or defer patients whose medical risk is too high, especially those with cardiovascular disease or other major contraindications. This is central to safer administration according to the source.

2 roles · 1 guidelines · 0 courses · 0 providers

Competence with open-label continuation procedures

Understand the transition from blinded randomized treatment to open-label MDMA-assisted therapy for eligible participants. This includes separate consent, revised scheduling, and altered assessment timing.

1 role · 1 guidelines · 0 courses · 0 providers

Conduct structured follow-up assessments

After completion of PE, patients are assessed over a 3-month follow-up period at multiple time points, requiring clinician or facilitator competence in longitudinal follow-up procedures. This includes maintaining contact and collecting outcome information consistently.

1 role · 1 guidelines · 0 courses · 0 providers

Confidential and accurate data collection

Collects and records substance use, withdrawal, and follow-up data accurately and responsibly in clinical or research settings.

2 roles · 1 guidelines · 0 courses · 0 providers

Contraindication identification

Knows the conditions that may disqualify a person from ketamine treatment and can apply that knowledge during screening. Recognizes medical, psychiatric, pregnancy-related, and substance-related contraindications.

2 roles · 1 guidelines · 0 courses · 0 providers

Contribute to treatment acceptability assessment

Clinicians should be able to evaluate and support treatment acceptability from both participant and clinician perspectives. The pilot reported high acceptability ratings by participants and study clinicians.

2 roles · 1 guidelines · 0 courses · 0 providers

COVID-19 infection control

Implement infection-prevention procedures during in-person study and dosing visits. Facilitators must screen participants, use PPE, maintain distancing when feasible, and adapt procedures based on test results or symptoms.

2 roles · 1 guidelines · 0 courses · 0 providers

Documentation and note-taking

Document participant experiences and relevant observations to support continuity, recall, and study integrity. Notes may also serve as a participant memory aid after dosing sessions.

2 roles · 1 guidelines · 0 courses · 0 providers

Eating disorder clinical knowledge

Knowledge of anorexia nervosa symptomatology, risk, and clinical instability relevant to screening and treatment monitoring. The study requires awareness of eating-disorder-specific risks and outcomes.

2 roles · 1 guidelines · 0 courses · 0 providers

Electrolyte and medical screening

Assess for physiologic factors that may increase ibogaine-related harm, especially electrolyte abnormalities. The source identifies electrolyte screening as part of safer administration.

2 roles · 1 guidelines · 0 courses · 0 providers

Eligibility documentation and accountability

Document eligibility decisions, registrations, and protocol compliance accurately and completely. This includes signed checklists, source documentation, and investigator attestation.

2 roles · 1 guidelines · 0 courses · 0 providers

Ethical handling of participant communication about future research

Manage optional future-contact procedures ethically and separately from current study participation. Participants may choose whether to authorize future contact without affecting present enrollment decisions.

2 roles · 1 guidelines · 0 courses · 0 providers

Evaluate readiness and contraindications for subsequent sessions

After each MDMA session, therapists must assess whether continuing treatment is safe and clinically appropriate. The participant’s choice is respected unless safety concerns warrant exclusion.

1 role · 1 guidelines · 0 courses · 0 providers

Hydration management

Prevent dehydration during and after ibogaine treatment. The manual stresses that patients may not feel like drinking and that dehydration can become dangerous, especially if vomiting occurs.

2 roles · 1 guidelines · 0 courses · 0 providers

Imaging and procedure-related awareness

Understands the implications of PET, MRI, blood sampling, and TMS-EEG procedures for participant comfort and safety. While not necessarily performing these procedures, the therapist/facilitator should know their risks and scheduling constraints.

2 roles · 1 guidelines · 0 courses · 0 providers

Inclusivity and non-discrimination in participant engagement

Therapist/facilitator practice in the study must align with equity, diversity, and inclusion commitments by avoiding exclusions based on protected or social identity characteristics outside protocol-defined scientific/safety criteria. This supports ethically sound participant engagement.

2 roles · 1 guidelines · 0 courses · 0 providers

Interpretation of autonomic effects

Understand that classic psychedelics can cause moderate increases in blood pressure, heart rate, temperature, and pupil size without necessarily indicating severe toxicity. Proper interpretation helps avoid overreaction while remaining vigilant.

2 roles · 1 guidelines · 0 courses · 0 providers

Interpretation of neuroimaging-linked clinical findings

Understand that changes in cerebral blood flow were observed after ayahuasca intake in regions implicated in mood and emotion regulation. Facilitators should be able to contextualize these findings without overinterpreting them clinically.

2 roles · 1 guidelines · 0 courses · 0 providers

Interprofessional coordination and referral management

Safe delivery requires coordination among therapists, physicians, nurses, blinded assessors, outside therapists, and emergency services.

2 roles · 1 guidelines · 0 courses · 0 providers

Intoxication assessment before preparation

Determine whether a patient is intoxicated enough to impair participation in preparation sessions. This requires clinical judgment focused on comprehension and therapeutic alliance.

1 role · 1 guidelines · 0 courses · 0 providers

Knowledge of psychedelic session structure

Facilitators need to understand the full treatment sequence and how each phase contributes to safety and treatment delivery. The intervention depends on correct sequencing and timing.

2 roles · 1 guidelines · 0 courses · 0 providers

Lost-to-follow-up procedures

The facilitator must make repeated documented efforts to contact participants who miss visits. Follow-up processes differ for responders and non-responders.

1 role · 1 guidelines · 0 courses · 0 providers

Management of dual relationships and undue influence

Therapists must protect voluntariness when potential participants are also their patients. Independent evaluation should be used to reduce pressure or perceived coercion in recruitment and consent.

2 roles · 1 guidelines · 0 courses · 0 providers

Managing short-duration high-intensity sessions

5-MeO-DMT produces a very short but intense experience, which changes facilitation demands. Facilitators must be prepared for rapid transitions into and out of the altered state.

1 role · 1 guidelines · 0 courses · 0 providers

Medical contraindication screening

Recognizes medical factors that may increase risk during inhaled 5-MeO-DMT administration. Medical clearance is required before dosing.

2 roles · 1 guidelines · 0 courses · 0 providers

Medication and interaction review

Identify concurrent medications or recent drug exposures that may interact dangerously with ibogaine. The clinician/facilitator must understand that ibogaine can potentiate other drugs and that certain psychiatric medications or toxic agents may contraindicate treatment.

2 roles · 1 guidelines · 0 courses · 0 providers

Medication interaction screening

Screen for co-medications that may prolong QTc or affect CYP2D6 metabolism. This is critical to reduce confounding and prevent additive toxicity.

2 roles · 1 guidelines · 0 courses · 0 providers

Medication reconciliation and interaction management

Therapists must understand clinically significant drug interactions with ibogaine, including QT-prolonging, serotonergic, centrally acting, and CYP2D6-related medications. This knowledge informs screening, tapering, and dosing decisions.

2 roles · 1 guidelines · 0 courses · 0 providers

Motivational interviewing

Uses an open, collaborative MI style to engage participants and support change. Employs reflective listening, eliciting change talk, and reinforcing motivation without confrontation.

2 roles · 1 guidelines · 0 courses · 0 providers

Neurologic adverse effect monitoring

Monitor for cerebellar toxicity and gait disturbance because severe transient ataxia was observed in all patients in the study. The facilitator must be able to detect impaired coordination and prevent falls or injury.

1 role · 1 guidelines · 0 courses · 0 providers

Operational prioritization of assessments

Sequences study procedures correctly to reduce bias and protect participant safety. Particularly prioritizes PROs, clinician ratings, and dosing-day procedures in the required order.

2 roles · 1 guidelines · 0 courses · 0 providers

Opioid use disorder assessment

Understands the clinical profile of opioid use disorder and identifies individuals with opioid dependence who may be considered for ibogaine-based detoxification in observational or treatment settings.

2 roles · 1 guidelines · 0 courses · 0 providers

Participant preparation and procedural guidance

Prepare participants for the dosing session and guide them through standardized procedures. The facilitator should ensure readiness, adherence to study rules, and smooth progression through the session schedule.

1 role · 1 guidelines · 0 courses · 0 providers

Participant screening and selection

Clinicians must identify appropriate participants and recognize that the study enrolled psychiatrically healthy nicotine-dependent smokers. Competence includes screening for psychiatric suitability and tobacco dependence characteristics relevant to treatment eligibility.

2 roles · 1 guidelines · 0 courses · 0 providers

Pre-session medical screening

The therapist/facilitator must ensure medical suitability before ayahuasca administration by checking for conditions that increase risk. Screening should include physical exam, laboratory testing, and pregnancy assessment when indicated.

2 roles · 1 guidelines · 0 courses · 0 providers

Professional ethics and policy adherence

Adheres to organizational code of ethics, privacy policy, electronic communication policy, and applicable laws. Maintains professional conduct across contractor and clinic arrangements.

2 roles · 1 guidelines · 0 courses · 0 providers

Protocol adherence and dose conditions

Follows the study's operational rules for dose timing, progression, and stopping conditions. Reliable execution is necessary for both safety and interpretability of results.

2 roles · 1 guidelines · 0 courses · 0 providers

Psychedelic pharmacology and interaction awareness

Understand the pharmacology and interaction risks of 5-MeO-DMT/BPL-003, including serotonergic and cardiovascular concerns. This knowledge informs safe preparation, exclusion screening, and monitoring.

2 roles · 1 guidelines · 0 courses · 0 providers

Psychiatric assessment using structured interviews

Conduct or support psychiatric screening using clinical interviews and structured diagnostic tools. The goal is to establish baseline mental health status and detect exclusionary disorders or instability.

2 roles · 1 guidelines · 0 courses · 0 providers

Qualified psychiatric interview

Conducts a retrospective psychiatric interview to judge minimal clinical improvement on the current antidepressant regimen. Uses multiple information sources and clinical observation to determine whether the participant meets screening requirements.

1 role · 1 guidelines · 0 courses · 0 providers

Reactivation event assessment

Identify and document possible post-dose reactivation or flashback-like experiences. The therapist must capture timing, context, emotional valence, and functional impact of these events.

1 role · 1 guidelines · 0 courses · 0 providers

Recognition of contraindications and medication interactions

Facilitators need knowledge of conditions and medications that may make 5-MeO-DMT unsafe or inappropriate. They should identify possible interactions and discuss them clearly before participation.

2 roles · 1 guidelines · 0 courses · 0 providers

Research visit scheduling and follow-up coordination

Coordinate multi-visit assessment timelines around the psilocybin session. Follow-up data collection is essential for longitudinal outcomes and requires careful scheduling.

2 roles · 1 guidelines · 0 courses · 0 providers

Research-professional role separation

Distinguish psychotherapy/facilitation functions from outcome assessment and other research tasks. Separation reduces bias and protects the integrity of blinded assessments.

2 roles · 1 guidelines · 0 courses · 0 providers

Risk and contraindication screening

Facilitators must know the risks and contraindications associated with ayahuasca use. They should identify medical and psychological factors that make participation unsafe or require extra caution.

2 roles · 1 guidelines · 0 courses · 0 providers

Safety escalation and collaboration

Knows when to involve physicians, psychologists, and independent safety oversight. Complex psychedelic sessions require clear escalation pathways and team coordination.

1 role · 1 guidelines · 0 courses · 0 providers

Session-day eligibility and compliance checks

Clinicians must ensure participants meet day-of-session safety requirements before psilocybin is administered. This includes verifying toxicology, pregnancy, alcohol abstinence, and adherence to protocol restrictions.

2 roles · 1 guidelines · 0 courses · 0 providers

Social support assessment and guidance

Therapists must assess the participant’s social support network and help plan appropriate use of supportive relationships during treatment. They should guide participants about the potential benefits and risks of sharing their experiences with others.

1 role · 1 guidelines · 0 courses · 0 providers

Structured psychiatric screening collaboration

Understands the screening instruments and the respective roles of site staff and independent raters. The facilitator must collaborate with rater findings while maintaining appropriate boundaries and blinding.

3 roles · 1 guidelines · 0 courses · 0 providers

Study design integrity

Supports rigorous conduct of randomized controlled safety studies by maintaining protocol adherence and minimizing bias. Protects the validity of safety, tolerability, and exploratory efficacy assessments.

2 roles · 1 guidelines · 0 courses · 0 providers

Suitability judgment

Organizers must decide whether to accept or refuse participants based on screening and interview data. When in doubt, the guidance favors non-acceptance.

1 role · 1 guidelines · 0 courses · 0 providers

Task instruction and coaching

Prepare participants to complete emotional processing tasks and questionnaires accurately. Staff must teach task procedures and ensure participants understand expectations before scanning and follow-up assessments.

2 roles · 1 guidelines · 0 courses · 0 providers

Telephone eligibility screening

Ability to conduct initial phone-based screening to determine whether a potential participant appears eligible for the protocol. This requires efficient, accurate triage before in-person assessment.

2 roles · 1 guidelines · 0 courses · 0 providers

Trauma-informed and emotionally sensitive interviewing

Conducts evaluations and psychotherapy with sensitivity to distress, moral injury, grief, and burnout. The therapist must avoid unnecessary burden while still collecting required data.

1 role · 1 guidelines · 0 courses · 0 providers

Understand psilocybin-assisted therapy as a rapid-acting intervention for depression

Facilitators require knowledge of the therapeutic context, including that psilocybin is being investigated as a rapid-acting treatment for major depressive disorder. This includes understanding the expected timeframe of symptom assessment and response.

1 role · 1 guidelines · 0 courses · 0 providers

Understanding of bipolar-specific risk context

The facilitator must understand why bipolar II participants require enhanced monitoring and conservative dosing. The protocol is built around the risk of mood destabilization in this population.

1 role · 1 guidelines · 0 courses · 0 providers

Understanding of study schedule and visit procedures

Facilitators must know the study timeline to conduct therapy and safety checks at the correct times. They should understand which visits are in person, virtual, or questionnaire-only and what assessments occur at each stage.

1 role · 1 guidelines · 0 courses · 0 providers

Use of cognitive and behavioral assessment domains

Understand the domains assessed in the Storyline psychiatric and neurological interviews and use this knowledge to support accurate administration and interpretation of study tasks. Domains include cognition, mood, homeostasis, social support, and psychosis/suicidality screening.

2 roles · 1 guidelines · 0 courses · 0 providers

Use of observation and assessment tools

The therapist should assess both the immediate experience and longer-term change, using structured observation, self-report, and reports from others where possible. The handbook treats evaluation as difficult but necessary for understanding therapeutic effects.

1 role · 1 guidelines · 0 courses · 0 providers

Use of recordings for qualitative analysis and fidelity review

The protocol depends on video/audio recordings for later transcription, qualitative coding, and adherence review. Staff must understand how these recordings support both science and supervision.

1 role · 1 guidelines · 0 courses · 0 providers

Use patient-reported outcomes in clinical evaluation

The study relied on self-reported symptomatology, so clinicians should understand how to gather and interpret patient-reported outcomes relevant to psychiatric and existential distress. This includes using subjective reports as meaningful indicators while recognizing their limits.

2 roles · 1 guidelines · 0 courses · 0 providers

Case-based practice, peer consultation, and professional learning community

Teaches applied competence through role play, case discussion, peer consultation, seminars, mentorship, and learning-community structures. The emphasis is translating theory into practice, receiving feedback, and developing reflective clinical judgment with peers.

7 roles · 0 guidelines · 8 courses · 7 providers

Psychedelic therapy foundation

Cluster covering 7 related competencies including: Psychedelic therapy foundation, Psychedelic therapy foundations, Psychedelic practice fundamentals.

7 roles · 0 guidelines · 6 courses · 5 providers

Ethics and ethical practice

Cluster covering 4 related competencies including: Ethical practice, Ethics in psychedelic care, Ethics and ethical practice.

6 roles · 0 guidelines · 4 courses · 3 providers

Clinical protocol literacy

Teaches practitioners to read and understand clinical protocols, treatment manuals, and evidence-based psychedelic care procedures. The focus is knowing how protocol requirements shape preparation, dosing, integration, documentation, and safety responsibilities.

6 roles · 0 guidelines · 2 courses · 2 providers

Complex-case support and ethics-based clinical judgment

Teaches work with clinically complex contexts such as trauma, palliative care, and other nuanced presentations where ethical judgment, scope discipline, careful assessment, and individualized support are required.

4 roles · 0 guidelines · 2 courses · 1 providers

Legal access pathways and care-team coordination

Teaches how participants move through lawful access routes and coordinated care pathways. The competency covers referral navigation, team handoffs, and the practical steps needed to connect eligible participants with appropriate treatment or study settings.

6 roles · 0 guidelines · 2 courses · 1 providers

Psilocybin prescribing fundamentals

Cluster covering 2 related competencies including: Psilocybin prescribing fundamentals, Prescribing fundamentals for psychedelic treatment.

2 roles · 0 guidelines · 2 courses · 1 providers

Assessment and intake

The curriculum includes practical assessment work and use of intake templates and assessment forms. Students learn to evaluate client fit and tailor support based on client goals and needs.

3 roles · 0 guidelines · 1 courses · 1 providers

Clinical documentation and coordination

Some listed programs explicitly teach clinical documentation and related practice management skills. This suggests learners may be expected to document care, coordinate treatment processes, and work within structured clinical workflows.

3 roles · 0 guidelines · 1 courses · 1 providers

Clinical trial training and feedback use

The page highlights best-in-class clinical training for drug trials and AI-supported evaluation. Learners are expected to refine skills quickly and receive targeted feedback in training or evaluation contexts.

6 roles · 0 guidelines · 1 courses · 1 providers

Collaborative work with adjunctive clients

Learners are taught how to work with clients who already have an outside therapist and to coordinate closely with existing treatment. The course also mentions treatment flow for groups and couples.

3 roles · 0 guidelines · 1 courses · 1 providers

Collaborative-care role awareness

The program emphasizes that it prepares people for therapeutic and facilitative roles within a collaborative care framework, not independent medical practice. Learners are expected to understand role boundaries, especially around prescribing and administration.

5 roles · 0 guidelines · 1 courses · 1 providers

Compound comparison for therapeutic use

The course teaches learners to distinguish between classic psychedelics and emerging therapies within therapeutic applications. This is a foundational comparative literacy competency rather than a protocol-specific skill.

6 roles · 0 guidelines · 1 courses · 1 providers

Contraindication and interaction review

The page explicitly notes medication interactions, contraindications, and risk management for prescribers. This indicates training in identifying unsafe combinations and excluding or delaying treatment when needed.

2 roles · 0 guidelines · 1 courses · 1 providers

Coordination and documentation using checklists and manuals

The page repeatedly points learners to manuals, checklists, PDFs, and reference materials, indicating a practical emphasis on coordination and structured preparation. This suggests learners should be able to organize session materials and support process consistency.

4 roles · 0 guidelines · 1 courses · 1 providers

Debriefing and reflective practice

The practicum includes retreat team debriefs, supervisor meetings, and assessment presentations. This signals an expectation that learners can reflect on practice, receive feedback, and integrate learning.

5 roles · 0 guidelines · 1 courses · 1 providers

Equitable Access and Inclusive Service Delivery

Teaches providers to recognise access barriers and health disparities, adapt services for diverse participant needs, and deliver care in ways that are inclusive, accessible, culturally responsive, and practically reachable.

4 roles · 0 guidelines · 1 courses · 1 providers

Safety-oriented documentation and templates

Trainees receive templates such as consent and intake forms, informational documents, and guidelines, which implies competence in using standardized practice materials. The page also signals procedural support for safe and organized care delivery.

5 roles · 0 guidelines · 1 courses · 1 providers

Safety, ethics, and responsibility in expanded states work

The course explicitly states that facilitators are guided in safety, ethics, and responsibility. Learners are expected to recognize and manage the unique risks of working with altered states.

3 roles · 0 guidelines · 1 courses · 1 providers

Structured PAP process navigation

The course teaches the overall PAP workflow from screening through follow-up. Learners are expected to understand and explain each phase of treatment in a structured way.

4 roles · 0 guidelines · 1 courses · 1 providers

Supervised practicum and feedback integration

Students complete 50 supervised practicum hours and receive expert feedback while working with real clients. This is intended to translate theory into competent applied practice.

4 roles · 0 guidelines · 1 courses · 1 providers

Supporting diverse spiritual and community contexts

The program states it prepares facilitators to address the needs of clients, patients, or community members from diverse faith traditions and communities of origin. Learners are expected to adapt facilitation to varied settings and worldviews.

3 roles · 0 guidelines · 1 courses · 1 providers

Working within legal and approved site structures

The practicum requires placements at pre-approved sites and emphasizes legal and ethical standards. Learners are exposed to different settings, including clinical, retreat, and harm reduction organizations.

4 roles · 0 guidelines · 1 courses · 1 providers

Bilingual and bicultural engagement

The page explicitly signals the value of bilingual and bicultural heritage as a foundation for practice. This points to competence in communicating and relating across language and cultural context.

3 roles · 0 guidelines · 0 courses · 1 providers

Therapeutic support in patient care settings

The page highlights extensive patient care experience and a background in holistic counseling psychology, suggesting practical competence in supporting participants in clinical or care environments. This is more general care-setting competence than protocol-specific technique.

4 roles · 0 guidelines · 0 courses · 1 providers

General psychedelic-assisted practice skills

Catch-all cluster covering 189 general competencies for psychedelic-assisted clinical practice that did not group into a more specific category — including miscellaneous facilitation, monitoring, ethics, safety, regulatory awareness, group support, and program-specific skills not captured by dedicated clusters elsewhere.

8 roles · 45 guidelines · 27 courses · 18 providers