Risk monitoring

Informed consent, decisional capacity, autonomy, and withdrawal rights

Teaches how to obtain and maintain valid informed consent through clear disclosure, comprehension checks, capacity support, voluntariness, non-coercion, and respect for refusal or withdrawal. The competency also covers consent for screening procedures, recordings, collateral contact, rescue interventions, and documentation of the consent process.

4 roles · 59 guidelines · 0 courses · 0 providers

Confidentiality, privacy, and research data protection

Teaches protection of participant identity, sensitive clinical or occupational information, recordings, and research data. The competency covers coded identifiers, restricted access, secure handling, confidentiality safeguards, and privacy-preserving documentation.

5 roles · 53 guidelines · 0 courses · 0 providers

Screening, eligibility, and readiness assessment

Teaches how to assess clinical suitability before psychedelic or ketamine treatment, including medical and psychiatric screening, readiness evaluation, contraindication review, inclusion/exclusion criteria, and ongoing eligibility re-checks before dosing.

8 roles · 52 guidelines · 15 courses · 12 providers

Acute psychological response and emergency management during dosing

Cluster covering 35 related competencies for monitoring acute psychological effects, recognising and managing distress, crisis containment, emergency escalation, and rescue-medication coordination during psychedelic dosing sessions.

6 roles · 51 guidelines · 2 courses · 2 providers

Adverse event identification, documentation, and reporting

Teaches how to detect, elicit, document, and report adverse events and serious adverse events across the participant journey. The focus is accurate source documentation, regulatory reporting discipline, follow-up, and preservation of participant safety and trial integrity.

4 roles · 46 guidelines · 0 courses · 0 providers

Preparation and integration support

Cluster covering 31 related competencies including: Integration support, Integration therapy, Integration coaching.

7 roles · 43 guidelines · 18 courses · 14 providers

Suicide and serious psychiatric risk assessment

Teaches structured assessment of suicidal ideation, intent, psychiatric deterioration, and related high-risk presentations. Learners are trained to use appropriate tools, safety planning, emergency contacts, clinician access, and escalation pathways when risk is identified.

6 roles · 41 guidelines · 1 courses · 1 providers

Manual fidelity, protocol adherence, and deviation management

Teaches faithful delivery of manualized treatment and protocol-defined procedures while documenting and managing unavoidable deviations. The competency protects participant welfare, treatment consistency, data integrity, and sponsor oversight.

5 roles · 39 guidelines · 0 courses · 0 providers

Post-dose follow-up, safety monitoring, and retention support

Teaches ongoing participant contact after dosing to support stability, detect delayed adverse effects, maintain therapeutic containment, and sustain adherence to follow-up visits and outcome assessments.

5 roles · 37 guidelines · 0 courses · 0 providers

Discharge readiness, escort safety, and post-session supervision

Teaches how to determine when a participant is safe to leave after dosing and how to arrange appropriate supervision afterward. The competency covers psychological and physical stability, escort/support-person coordination, discharge restrictions, overnight or post-session support, and follow-up contact when needed.

4 roles · 30 guidelines · 0 courses · 0 providers

Emergency recognition, escalation, and disposition planning

Teaches recognition of medical or psychiatric emergencies and the steps required to escalate care safely. The competency includes de-escalation, clinical consultation, 911 or emergency department transfer, serious-event escalation, and referral to appropriate higher-level care.

7 roles · 29 guidelines · 3 courses · 3 providers

Blinding, allocation concealment, and unblinding control

Teaches how to preserve blinded trial conduct across participant interactions, outcome collection, staff roles, and session procedures. The competency includes preventing accidental unblinding, minimizing bias, and using emergency unblinding only when clinically necessary.

6 roles · 29 guidelines · 0 courses · 0 providers

Medication, substance-use, washout, and taper management

Teaches review and management of concomitant medications, restricted therapies, prohibited substances, washout periods, tapering requirements, and abstinence expectations. The competency includes participant counseling, medication reconciliation, sponsor notification, and team coordination when restrictions affect safety or interpretability.

5 roles · 29 guidelines · 0 courses · 0 providers

Study documentation, data integrity, and regulatory recordkeeping

Teaches accurate study documentation, source-record quality, secure data capture, Good Clinical Practice recordkeeping, IRB and sponsor documentation requirements, monitoring readiness, audit support, accountability, and retention obligations.

3 roles · 27 guidelines · 0 courses · 0 providers

Manualized psychedelic psychotherapy delivery

Teaches delivery of psychedelic-assisted psychotherapy according to an approved study manual across preparation, dosing, integration, and follow-up. The competency balances standardized structure with non-directive support for the participant’s therapeutic process.

4 roles · 25 guidelines · 3 courses · 2 providers

Therapeutic boundaries, professional conduct, and consent for touch

Teaches how to maintain clear relational and physical boundaries in emotionally vulnerable treatment settings. This includes professional conduct, rapport without overreach, explicit consent for touch, the right to revoke consent, and strict prohibition of sexual or erotic contact.

7 roles · 24 guidelines · 4 courses · 3 providers

Co-therapist and multidisciplinary team coordination

Teaches coordinated practice across co-therapists, physicians, psychiatrists, study coordinators, principal investigators, and other care-team members. The focus is shared responsibility, clear communication, role clarity, and coordinated observation of participant status.

4 roles · 24 guidelines · 0 courses · 0 providers

Study record and trial registration literacy

Teaches how to understand ClinicalTrials.gov records and related study information, including glossary terms, registration fields, protocol descriptors, and results-reporting elements used to interpret clinical research records.

3 roles · 24 guidelines · 0 courses · 0 providers

Physical safety monitoring

Cluster covering 3 related competencies including: Physical safety monitoring, Safety monitoring during dosing sessions, Medical safety monitoring during psilocybin administration.

5 roles · 19 guidelines · 0 courses · 0 providers

Acute psychiatric and behavioral risk monitoring

Teaches continuous monitoring for distress, confusion, psychotic symptoms, suicidality, agitation, and other acute behavioral risks during and after dosing. The focus is early recognition, documentation, and escalation to clinical support when risk emerges.

5 roles · 17 guidelines · 0 courses · 0 providers

Preparation support

Cluster covering 11 related competencies including: Preparation support, Psilocybin preparation, Therapeutic preparation.

3 roles · 16 guidelines · 6 courses · 5 providers

Ethical conduct in human-subject research

Able to practice ethically in a clinical trial environment involving a Schedule-sensitive psychoactive intervention. This includes protecting participants, adhering to protocol, and supporting valid informed participation.

3 roles · 16 guidelines · 0 courses · 0 providers

Supportive nondirective therapeutic stance

Cluster covering 6 related competencies including: Therapeutic support during dosing, Nondirective dosing-session presence, Supportive dosing-session facilitation.

2 roles · 16 guidelines · 0 courses · 0 providers

Therapeutic alliance building

Cluster covering 2 related competencies including: Therapeutic alliance building, Therapeutic alliance and rapport building.

2 roles · 15 guidelines · 1 courses · 1 providers

Good Clinical Practice and protocol procedure compliance

Teaches adherence to Good Clinical Practice, assigned study roles, protocol procedures, delegation boundaries, and applicable research regulations. The competency supports consistent execution of approved procedures across sites and participants.

4 roles · 15 guidelines · 0 courses · 0 providers

Psilocybin session facilitation

Cluster covering 9 related competencies including: Psilocybin facilitation, Psilocybin session support, Psilocybin facilitation basics.

6 roles · 14 guidelines · 6 courses · 5 providers

Adverse effects and side-effect management

Teaches recognition and management of expected and unexpected side effects during psychedelic or ketamine treatment. The competency emphasizes active observation, supportive response, and clinical escalation when symptoms exceed routine tolerability.

6 roles · 14 guidelines · 1 courses · 1 providers

Psychedelic-assisted psychotherapy preparation and integration

Teaches structured pre-dose preparation and post-dose integration as the therapeutic frame for psychedelic-assisted psychotherapy. The therapist supports rapport, intention clarification, meaning-making, emotional processing, and consolidation of insights after dosing.

6 roles · 13 guidelines · 2 courses · 2 providers

Hallucinogen pharmacology and effects

Cluster covering 7 related competencies including: Physiologic safety awareness, Hallucinogen pharmacology and effects, Hallucinogen-assisted therapy knowledge.

4 roles · 13 guidelines · 0 courses · 0 providers

Ketamine psychotherapy delivery

Cluster covering 12 related competencies including: KAP psychotherapy delivery, Ketamine and KAP knowledge, Ketamine integration planning.

6 roles · 12 guidelines · 7 courses · 5 providers

Dissociation and acute neuropsychiatric effect monitoring

Teaches recognition and documentation of dissociation, psychosis-like symptoms, mania, and other acute neuropsychiatric effects that can occur after ketamine, psychedelic dosing, or related interventions. The focus is monitoring, reporting, and escalation when symptoms become clinically significant.

5 roles · 12 guidelines · 0 courses · 0 providers

Physiologic monitoring, thermoregulation, hydration, and overdose response

Teaches monitoring and response for acute physiological risks, including vital signs, temperature, hydration, overheating, excessive fluid intake, and suspected overdose. The competency emphasizes supportive care, medical coordination, documentation, and escalation when needed.

6 roles · 11 guidelines · 0 courses · 0 providers

Special-interest adverse event vigilance

The protocol requires active monitoring for psychedelic-specific adverse events such as hallucinations, psychotic symptoms, dissociation, mood alteration, and cognitive disturbance. These require immediate notification and follow-up.

3 roles · 11 guidelines · 0 courses · 0 providers

Depression symptom and remission monitoring

Teaches structured monitoring of depressive symptoms, response, and remission across treatment and follow-up. Learners use standardized scales and clinical review to track change and identify deterioration or non-response.

2 roles · 10 guidelines · 0 courses · 0 providers

Mindfulness, intention-setting, set and setting, and somatic presence

Teaches practices that support preparation and therapeutic presence, including mindfulness, intention-setting, body-aware attention, environmental preparation, mindset awareness, and regulation through somatic presence.

6 roles · 9 guidelines · 7 courses · 6 providers

Trauma-informed therapeutic presence and somatic support

Teaches a trauma-informed stance during psychedelic work, including calm presence, non-verbal reassurance, body-aware support, somatic orientation, and containment through difficult experiences while maintaining safety and boundaries.

2 roles · 9 guidelines · 2 courses · 2 providers

Comprehensive psychiatric assessment

Ability to perform or supervise detailed psychiatric evaluation for diagnosis, eligibility, and ongoing monitoring. The therapist/facilitator must understand symptom presentations relevant to MDD, AUD, suicidality, psychosis, and dissociation.

3 roles · 9 guidelines · 0 courses · 0 providers

Ensure confidentiality and session containment

Maintain a contained therapeutic environment that protects the patient’s privacy and minimizes unwanted exposure. The session structure emphasizes confidentiality and controlled access to stimulation and outside contact.

2 roles · 9 guidelines · 0 courses · 0 providers

Grounding and regulation techniques

Therapists must be able to teach and coach grounding practices that help participants regulate during preparation and dosing. These methods are used before medication and during distress.

2 roles · 9 guidelines · 0 courses · 0 providers

Outcome Measure and Assessment Literacy

Teaches clinicians and research staff to understand the purpose, limits, scoring, interpretation, and clinical meaning of psychological measures and study instruments used to evaluate symptoms, functioning, safety, and treatment outcomes.

3 roles · 9 guidelines · 0 courses · 0 providers

Client preparation and therapeutic set/setting

Cluster covering 2 related competencies including: Preparation of set and setting, Client preparation and therapeutic set/setting.

3 roles · 8 guidelines · 2 courses · 2 providers

Continuation, discontinuation, and risk-benefit judgment

Teaches how clinicians determine whether a participant should proceed, pause, discontinue dosing, or terminate study participation. The competency centers on safety-driven clinical judgment, risk-benefit assessment, and early termination when continuation is no longer appropriate.

5 roles · 8 guidelines · 0 courses · 0 providers

Participant safety restriction counseling

Teaches how to instruct participants on post-dose and study-period restrictions that reduce risk from impaired judgment, unsafe activity, prohibited substances, or behaviors that could confound study outcomes.

3 roles · 8 guidelines · 0 courses · 0 providers

Physiologic monitoring during ketamine administration

Cluster covering 2 related competencies including: Safety monitoring during ketamine dosing, Physiologic monitoring during ketamine administration.

4 roles · 8 guidelines · 0 courses · 0 providers

Psychedelic-assisted therapy facilitation

Cluster covering 2 related competencies including: Psychedelic-assisted therapy facilitation, Group facilitation in a psychedelic setting.

3 roles · 8 guidelines · 0 courses · 0 providers

Psychological support during altered states

Provides supportive therapeutic presence while the patient is under the influence of ketamine. Uses calming, noncoercive guidance to help the patient navigate dissociation and emotional material.

3 roles · 8 guidelines · 0 courses · 0 providers

Training and competency maintenance

Therapists and study personnel are expected to receive structured training and ongoing supervision. Competence includes both protocol adherence and the ability to work safely and consistently across sites.

3 roles · 8 guidelines · 0 courses · 0 providers

Use outcome assessment and follow-up to evaluate response

The study used standardized anxiety measures and followed patients for 2 months and 12 months, implying competence in tracking outcomes over time. Therapists should be able to assess symptom change and sustained benefit using structured follow-up.

2 roles · 8 guidelines · 0 courses · 0 providers

Vital sign and physical distress monitoring

Monitors participant physical status during study visits and identifies concerning changes requiring escalation. Vital signs and symptomatic changes are part of routine safety observation.

4 roles · 8 guidelines · 0 courses · 0 providers

Cultural humility, Indigenous respect, and equity-oriented care

Teaches culturally responsive psychedelic care, including humility, anti-bias practice, Indigenous and traditional-use awareness, cultural appropriation concerns, diversity and inclusion, and respectful work with marginalized communities.

6 roles · 7 guidelines · 11 courses · 10 providers

Transference, countertransference, and therapist self-awareness

Teaches recognition and management of relational dynamics that can intensify in psychedelic-assisted therapy. Learners develop self-awareness around countertransference, projection, attachment, dependency, and other therapeutic-process risks.

3 roles · 7 guidelines · 1 courses · 1 providers

Clinical interviewing and history-taking

Therapists and study clinicians perform detailed biopsychosocial interviewing during preparation and screening. This supports treatment planning, risk assessment, and therapeutic understanding.

2 roles · 7 guidelines · 0 courses · 0 providers

Clinical Interviewing and PTSD Assessment

Teaches structured clinical interviewing and assessment administration for PTSD and related symptom domains, including symptom severity, functional impairment, risk factors, and appropriate use of standardized assessment tools.

2 roles · 7 guidelines · 0 courses · 0 providers

Dose escalation decision support

The therapist/facilitator must support structured dose escalation decisions within the individualized dosing regimen. Decisions depend on both patient-reported peak experience and clinical tolerability/safety judgments.

2 roles · 7 guidelines · 0 courses · 0 providers

Medical escalation and rescue medication coordination

Cluster covering 2 related competencies including: Medical escalation and rescue medication use, Medical escalation and rescue medication coordination.

4 roles · 7 guidelines · 0 courses · 0 providers

Participant-centered discharge planning and aftercare

Support decision-making about ongoing treatment after trial completion, particularly for participants who received escitalopram. The clinician helps participants consider whether to continue, taper, or return to usual care.

3 roles · 7 guidelines · 0 courses · 0 providers

Safe Therapeutic Container Creation

Teaches providers to create and maintain a psychologically and physically safe therapeutic setting through clear structure, preparation, boundaries, attunement, environmental design, and ongoing attention to participant safety.

4 roles · 6 guidelines · 2 courses · 2 providers

Integration and post-session debriefing

Cluster covering 4 related competencies including: Integration and debriefing, Integration and debriefing facilitation, Integration and post-session debriefing.

2 roles · 6 guidelines · 0 courses · 0 providers

Ketamine infusion monitoring

Cluster covering 5 related competencies including: Cardiac safety monitoring, Ketamine infusion monitoring, Ketamine infusion administration.

3 roles · 6 guidelines · 0 courses · 0 providers

Medical screening and medication review

Therapists/investigators must understand the medical suitability requirements for LSD-assisted psychotherapy and coordinate medication washout and concomitant medication review. This includes recognizing drug-drug interaction risks and contraindications.

3 roles · 6 guidelines · 0 courses · 0 providers

Medication taper and withdrawal monitoring

Teaches monitoring during down-titration or discontinuation of psychiatric medications before dosing. Learners track withdrawal symptoms, symptom worsening, suicidality, and other risks that may emerge during tapering.

4 roles · 6 guidelines · 0 courses · 0 providers

Professional boundaries and recording consent

Therapists may record sessions only with explicit participant consent and must handle recordings for training and research within protocol limits. Recording is part of the therapeutic and scientific framework, not routine clinical use.

3 roles · 6 guidelines · 0 courses · 0 providers

Reproductive risk, contraception, and pregnancy monitoring

Teaches counseling and monitoring around contraception, reproductive restrictions, pregnancy risk, and pregnancy-related discontinuation rules. Learners are trained to explain requirements clearly and respond promptly when pregnancy or reproductive-safety concerns arise.

2 roles · 6 guidelines · 0 courses · 0 providers

Safe treatment-setting facilitation

Provide a calm and supportive environment during treatment to reduce distress and support tolerance of the experience. The case report notes food, rest, and a quiet place as part of care.

2 roles · 6 guidelines · 0 courses · 0 providers

Therapeutic rapport building

Cluster covering 4 related competencies including: Therapeutic rapport building, Rapport building and trust development, Therapeutic rapport and trust building.

2 roles · 6 guidelines · 0 courses · 0 providers

Psilocybin psychotherapy framework

Cluster covering 4 related competencies including: Psychedelic therapy workflow, Psilocybin psychotherapy framework, Psilocybin-assisted psychotherapy framework.

6 roles · 5 guidelines · 4 courses · 2 providers

Ethical psychedelic facilitation

Cluster covering 3 related competencies including: Ethical psychedelic facilitation, Safe, legal psychedelic care facilitation, Ethical decision-making in psychedelic facilitation.

7 roles · 5 guidelines · 2 courses · 2 providers

Session facilitation and therapeutic holding

Cluster covering 2 related competencies including: Session facilitation and therapeutic holding, Session facilitation and support during intense experiences.

3 roles · 5 guidelines · 2 courses · 2 providers

Management of concomitant medication interactions

Cluster covering 5 related competencies including: Concomitant medication review, Contraindication and interaction awareness, Contraindications, drug effects, and interactions.

4 roles · 5 guidelines · 1 courses · 1 providers

Assessment administration and interpretation

Ability to administer and interpret structured interviews, clinician ratings, and self-report measures used in the study. Therapists contribute to eligibility, safety, and outcome assessment.

2 roles · 5 guidelines · 0 courses · 0 providers

Evaluate clinically significant response and treatment outcomes

Therapists/facilitators should be able to judge whether therapeutic change reaches clinically meaningful thresholds, not just whether symptoms improve numerically. This supports informed ongoing care and communication about benefits and limitations.

2 roles · 5 guidelines · 0 courses · 0 providers

Facilitate processing of difficult emotions

Therapists must help patients face and work through grief, fear, rage, panic, shame, guilt, and existential distress rather than avoid them. The clinician supports emotional expression while maintaining safety and meaning-making.

2 roles · 5 guidelines · 0 courses · 0 providers

Knowledge of PTSD and fear extinction theory

Understand the clinical and neurobehavioral rationale for PE and exposure-based treatment. The therapist should know how extinction learning is conceptualized in the study model.

2 roles · 5 guidelines · 0 courses · 0 providers

Match dose and setting to patient capacity

Therapists/facilitators need judgment about dosing and setting so experiences remain tolerable and therapeutically useful. The paper repeatedly notes that when dose and setting are appropriate, emerging material remains within the patient’s capacity to cope.

2 roles · 5 guidelines · 0 courses · 0 providers

Participant education and informed consent communication

Clinicians and research staff must clearly educate participants about study procedures, risks, side effects, restrictions, and possible benefits, and obtain written informed consent before screening and study participation. Ethical delivery depends on transparent communication and opportunities for questions.

2 roles · 5 guidelines · 0 courses · 0 providers

Participant safety planning and support network coordination

Can identify and involve support persons, attendants, and outside providers to enhance safety. The facilitator must coordinate practical supports while respecting confidentiality and protocol boundaries.

3 roles · 5 guidelines · 0 courses · 0 providers

Provide overnight and next-day containment

Therapists must ensure continuity of care after the acute session, including overnight observation and next-morning integration before discharge. This reflects a containment and recovery responsibility beyond the dosing period.

3 roles · 5 guidelines · 0 courses · 0 providers

Research assessment administration

Administer study measures and structured assessments on schedule, including psychological, spiritual, and neurobehavioral instruments. This includes both paper-based and Storyline-based assessments.

2 roles · 5 guidelines · 0 courses · 0 providers

Respect autonomy and individualized communication preferences

Adapt language and interpersonal style to the patient’s preferences to promote dignity and comfort. The therapist should also respect the patient’s autonomy within safety limits.

2 roles · 5 guidelines · 0 courses · 0 providers

Risk screening and exclusion judgment

Know the medical and psychiatric exclusions that protect participants from foreseeable harm. Facilitators must recognize conditions that make MDMA-assisted psychotherapy unsafe or inappropriate.

3 roles · 5 guidelines · 0 courses · 0 providers

Trauma-focused exposure facilitation

Facilitate trauma exposure in a structured, supportive, and protocol-consistent manner. The therapist must be able to initiate, pace, and process exposure work while maintaining adherence to PE methods.

2 roles · 5 guidelines · 0 courses · 0 providers

Understand dose-response and time course

The facilitator should know how oral and intravenous dosing relate to onset, duration, and peak effects. This knowledge supports proper session planning, monitoring, and integration timing.

2 roles · 5 guidelines · 0 courses · 0 providers

Professional self-care and burnout prevention

Teaches sustainable self-care practices for clinicians and facilitators working in emotionally intense settings. The competency supports emotional resilience, ethical boundaries, reflective practice, and burnout prevention.

5 roles · 4 guidelines · 3 courses · 3 providers

Risk evaluation and safety monitoring

Teaches continuous evaluation of clinical risk and maintenance of a safe care environment throughout preparation, dosing, and follow-up. Learners monitor risk signals, apply safety procedures, and escalate care when needed.

6 roles · 4 guidelines · 3 courses · 2 providers

Music and therapist-variable awareness

The course explicitly mentions the role of music and therapist variables in treatment. Learners are expected to understand how these elements influence the PAP experience and therapeutic outcome.

3 roles · 4 guidelines · 1 courses · 1 providers

Therapeutic touch judgment

The training includes appropriate use of therapeutic touch as part of safe delivery. Learners are expected to use touch judiciously and within ethical boundaries.

4 roles · 4 guidelines · 1 courses · 1 providers

Addiction and OUD treatment knowledge

Facilitator must understand opioid use disorder, medication-assisted treatment, and the clinical rationale for adjunctive psychotherapy. The protocol frames MORE+KAP as an investigational augmentation to buprenorphine treatment.

2 roles · 4 guidelines · 0 courses · 0 providers

Controlled-substance handling awareness

Understands that MDMA is a Schedule 1 investigational product and must be stored, dispensed, and accounted for under regulatory control. Supports compliant handling during the session.

2 roles · 4 guidelines · 0 courses · 0 providers

Dosage judgment and administration safety

Competent facilitation requires practical knowledge of dosage ranges, initial dosing, boosters, formulation handling, and administration errors. The handbook stresses both clinical judgment and meticulous procedural care.

2 roles · 4 guidelines · 0 courses · 0 providers

Manage agitation and elopement risk

Respond to agitation or attempts to leave the room in a way that preserves safety for the patient and others. The therapist should use containment, redirection, and escalation protocols when needed.

3 roles · 4 guidelines · 0 courses · 0 providers

Management of residual symptoms and re-entry

Therapists must prepare the subject for residual effects after the main session and provide practical safeguards for sleep, transportation, and home support. This includes framing recurrence of symptoms in a non-alarming way.

2 roles · 4 guidelines · 0 courses · 0 providers

MDMA administration oversight

Study clinicians are responsible for administering study drug, ensuring correct dose assignment, and supervising safe oral ingestion during blinded sessions. This includes verifying visit-specific randomization information and ensuring dosing is delivered under the blinded workflow.

2 roles · 4 guidelines · 0 courses · 0 providers

Monitor acute and short-term adverse effects

The study emphasizes the absence of acute or chronic adverse effects persisting beyond 1 day and no treatment-related serious adverse events, indicating the need for active monitoring during and after treatment. Facilitators must be able to observe, document, and respond to adverse reactions.

2 roles · 4 guidelines · 0 courses · 0 providers

Nonintrusive session monitoring and containment

Facilitators must balance active safety monitoring with minimal interference in the participant’s inner experience. The role includes maintaining continuous presence, periodic check-ins, and preserving the therapeutic container of the session.

2 roles · 4 guidelines · 0 courses · 0 providers

Pre-session dosing behavior instructions

Teaches clear communication of behavioral requirements before dosing sessions so conditions are standardized and preventable risks are reduced. Staff confirm that participants understand and follow pre-session instructions.

3 roles · 4 guidelines · 0 courses · 0 providers

Prioritize participant wellbeing over research aims

Participant safety and wellbeing must take precedence over scientific objectives at all times. Therapists must communicate and operationalize this priority throughout screening, treatment, and follow-up.

3 roles · 4 guidelines · 0 courses · 0 providers

Psilocybin psychoeducation

Cluster covering 2 related competencies including: Psilocybin psychoeducation, Psychedelic psychoeducation and expectation management.

2 roles · 4 guidelines · 0 courses · 0 providers

Recognition of contraindications and risk states

Therapists/facilitators must know the psychiatric and medical conditions that make KPT unsafe or inappropriate. Safe practice depends on excluding high-risk individuals.

2 roles · 4 guidelines · 0 courses · 0 providers

Recognize limits of evidence and avoid overstatement

Therapists and facilitators should communicate treatment effects responsibly and acknowledge methodological limitations. The paper notes small sample size, lack of long-term control group, and need for further study of mechanisms.

2 roles · 4 guidelines · 0 courses · 0 providers

Respect for cultural and indigenous context

The use of ayahuasca requires sensitivity to its traditional indigenous and ceremonial origins. Facilitators should avoid reducing the practice to a purely technical intervention and should respect cultural meaning and ceremonial context.

2 roles · 4 guidelines · 0 courses · 0 providers

Structured symptom rating administration

Facilitators must competently administer and interpret clinician-rated ADHD and global severity measures. Accurate scoring is essential because these scales determine eligibility and outcomes.

3 roles · 4 guidelines · 0 courses · 0 providers

Substance use assessment

Ability to evaluate alcohol and other substance use patterns using standardized tools and clinical interview. This is essential for eligibility, safety, and outcome monitoring.

2 roles · 4 guidelines · 0 courses · 0 providers

Crisis and adverse-event response

The page signals training in managing difficult or high-risk moments, including crisis intervention and trigger management. Learners are expected to respond appropriately when a session becomes destabilizing or unsafe.

6 roles · 3 guidelines · 1 courses · 1 providers

Safety monitoring and emergency awareness

The page points to checklists and a guide to basic medical emergencies, indicating that learners should be able to monitor safety and recognize urgent issues. The overall training context also stresses keeping both client and practitioner safe.

5 roles · 3 guidelines · 1 courses · 1 providers

Assess outcomes and psychological change

The framework implies competence in evaluating both symptom change and subjective outcomes over time. The study used standardized anxiety measures and qualitative interviews to assess sustained effects and patient-reported change.

2 roles · 3 guidelines · 0 courses · 0 providers

Attendant supervision and role clarity

Therapists must ensure attendants are appropriately selected and instructed for overnight monitoring. Attendants provide supportive care and observation without taking on psychotherapeutic functions.

3 roles · 3 guidelines · 0 courses · 0 providers

Balance inner focus with communication

Therapists should support an appropriate rhythm between inward experiential focus and verbal interaction, with either therapist or participant able to initiate shifts.

2 roles · 3 guidelines · 0 courses · 0 providers

Behavioral monitoring and outcome assessment

Collect smoking-related behavioral data and participant-reported outcomes repeatedly across the trial. Facilitators must accurately gather self-report, breath CO, urine, and questionnaire data according to protocol.

3 roles · 3 guidelines · 0 courses · 0 providers

Blinded Assessment and Independent Rating

Teaches the use of independent or blinded assessors to reduce expectancy and observer bias, preserve separation between therapeutic and rating roles, manage unblinding risks, and protect outcome validity in open-label or partially blinded designs.

3 roles · 3 guidelines · 0 courses · 0 providers

Cardiac risk monitoring

Monitor for ibogaine-associated cardiac toxicity, especially QTc prolongation and risk of torsades de pointes. This includes baseline exclusion screening, frequent ECG surveillance, and escalation when QTc becomes markedly prolonged.

2 roles · 3 guidelines · 0 courses · 0 providers

Empathic presence and listening

Therapists must listen with nonjudgmental, emotionally attuned presence and convey validation, reassurance, and curiosity. They should be able to stay relaxed yet engaged, including noticing nonverbal cues and responding without prying.

2 roles · 3 guidelines · 0 courses · 0 providers

Expectation and expectancy management

Understand how treatment expectations can influence treatment response and study interpretation. Facilitation must avoid inadvertently shaping expectations in a biased or misleading way.

2 roles · 3 guidelines · 0 courses · 0 providers

Handle altered, irrational, or hallucinatory narratives without invalidation

Accept the patient’s experience as meaningful without disputing or forcing interpretation. The therapist supports reflection while avoiding premature conclusions about reality or correctness.

2 roles · 3 guidelines · 0 courses · 0 providers

Informed consent and treatment briefing

Therapists/facilitators must support ethically valid informed consent by ensuring participants understand the intervention, expectations, risks, and logistics. They also provide anticipatory guidance before ketamine sessions and discharge information after dosing.

2 roles · 3 guidelines · 0 courses · 0 providers

Informed consent responsibility

Facilitators are responsible for ensuring that participants have provided informed consent before receiving MDMA-assisted therapy. This reflects an ethical and regulatory duty central to work with investigational treatments.

2 roles · 3 guidelines · 0 courses · 0 providers

Informed preparation and orientation of the subject

The therapist is responsible for giving truthful, individualized preparation and reassurance about the experience, including likely sensations, risks of resistance, and expectations for conduct. The preparation aims to reduce fear, improve cooperation, and support voluntary participation.

2 roles · 3 guidelines · 0 courses · 0 providers

Interdisciplinary coordination across mental health and medical services

Combined ketamine infusion and PE treatment requires coordination between psychotherapy providers and medical/anesthesia or medication administration staff. Effective collaboration supports timing, safety oversight, and protocol fidelity.

3 roles · 3 guidelines · 0 courses · 0 providers

Knowledge of ayahuasca pharmacology and effects

Understand the basic pharmacology and clinical effects of ayahuasca to inform safe facilitation and interpretation of responses. The source identifies dimethyltryptamine as a 5-HT2A agonist and harmine as a monoamine-oxidase A inhibitor.

2 roles · 3 guidelines · 0 courses · 0 providers

Knowledge of MDMA effects and risks

Facilitators must understand the expected psychological, physiological, and potential adverse effects of MDMA in order to prepare participants, support the session, and detect complications.

3 roles · 3 guidelines · 0 courses · 0 providers

Laboratory and ECG safety review

Reviews laboratory and ECG data for clinically relevant abnormalities and determines whether continued participation is appropriate. Escalates abnormalities requiring repeat testing or specialist input.

2 roles · 3 guidelines · 0 courses · 0 providers

Maintain scientific and ethical caution in representing benefits

Because the paper notes limited conclusions about efficacy due to the crossover design, clinicians have an ethical responsibility to avoid overstating treatment effects. Competence includes accurately presenting the evidence base, uncertainty, and limits of inference to patients and colleagues.

2 roles · 3 guidelines · 0 courses · 0 providers

MRI safety screening and imaging-session coordination

Teaches screening for MRI contraindications and coordination of imaging clearance before scan procedures. The competency prevents exposure of ineligible participants to magnetic-resonance risks and supports safe imaging-session logistics.

3 roles · 3 guidelines · 0 courses · 0 providers

No extractable therapist/facilitator competencies in provided source text

The provided source text is only a ClinicalTrials.gov interface/header snippet and does not contain study intervention procedures, therapist qualifications, facilitator responsibilities, safety monitoring procedures, or ethical guidance specific to clinical practice.

2 roles · 3 guidelines · 0 courses · 0 providers

Opioid withdrawal assessment

Evaluates opioid withdrawal symptoms and tracks changes over time in participants discontinuing methadone OST. Uses standardized withdrawal ratings to assess potential treatment effects and safety.

2 roles · 3 guidelines · 0 courses · 0 providers

Pre-treatment clinical risk assessment

Understand the major medical risks associated with ibogaine administration, especially cardiac and neurologic toxicity, before proceeding with treatment. This includes recognizing that ibogaine has been linked to torsades de pointes, QTc prolongation, bradycardia, and ataxia.

3 roles · 3 guidelines · 0 courses · 0 providers

Psychoeducation about MDMA effects and session trajectory

Therapists must understand MDMA’s expected subjective, interpersonal, and physiological effects and prepare participants accordingly. This knowledge supports normalization, reassurance, and effective use of the medicine within therapy.

2 roles · 3 guidelines · 0 courses · 0 providers

Psychological state assessment

Administer and interpret psychological and psychometric measures relevant to mood, cravings, expectations, mystical experience, ego dissolution, and functioning. Facilitators must accurately support questionnaire-based assessment across time points.

2 roles · 3 guidelines · 0 courses · 0 providers

Research rating fidelity

Ability to administer standardized clinical ratings consistently and under supervision. Reliable measurement is essential for efficacy and safety endpoints.

4 roles · 3 guidelines · 0 courses · 0 providers

Safety monitoring of vital signs and cardiovascular effects

Monitor and respond to the expected sympathomimetic effects of MDMA. The therapist/facilitator must be alert to transient increases in blood pressure, pulse, and related cardiac symptoms.

2 roles · 3 guidelines · 0 courses · 0 providers

Setting optimization

Create an environment that supports safety, comfort, and relaxation during the session. The setting is deliberately structured to reduce anxiety and facilitate a positive experience.

2 roles · 3 guidelines · 0 courses · 0 providers

Special population sensitivity in advanced cancer

Tailor therapeutic engagement to patients with advanced non-operable GI cancers facing existential distress, grief, and limited life expectancy. The therapist/facilitator must recognize the emotional and medical context of end-of-life suffering.

2 roles · 3 guidelines · 0 courses · 0 providers

Substance use relapse monitoring

Ability to monitor for opioid use recurrence, other substance use, and ketamine misuse during the trial. The clinician must recognize relapse risk and take action when substance use worsens.

2 roles · 3 guidelines · 0 courses · 0 providers

Support peak or mystical-type experiences without imposing them

Facilitators should be able to contain and make therapeutic use of profound emotional or peak experiences, including ego loosening, awe, reassurance, and feelings of unity or peace. The article suggests these experiences can be highly meaningful and therapeutic, but not all need to meet full mystical criteria.

2 roles · 3 guidelines · 0 courses · 0 providers

Support safe administration of LSD dosing sessions

Because the protocol involved specific LSD doses, active placebo control, and session spacing, facilitators need applied skill in implementing dosing-session procedures safely and consistently. This includes maintaining therapeutic support while adhering to protocol constraints.

2 roles · 3 guidelines · 0 courses · 0 providers

Support structured symptom monitoring

Although formal measurements may be conducted by another researcher, therapists/facilitators must work within a protocol that includes repeated anxiety assessments and daily diaries of anxiety, pain, and medication use. This implies competence in reinforcing adherence to monitoring procedures and integrating findings into care awareness.

2 roles · 3 guidelines · 0 courses · 0 providers

Teach and apply stress inoculation and anxiety support

Therapists should identify or teach in-session coping tools and collaboratively plan how anxiety states will be recognized and supported.

2 roles · 3 guidelines · 0 courses · 0 providers

Therapeutic alliance and trust building

The therapist must create an atmosphere of confidence and mutual understanding before ketamine administration. This relationship is treated as a key therapeutic factor in the protocol.

1 role · 3 guidelines · 0 courses · 0 providers

Therapeutic rapport and engagement support

Help patients engage in emotionally intense trauma-focused treatment and reduce dropout risk. The therapist should recognize comorbid depression or anxiety that may interfere with adherence and response.

2 roles · 3 guidelines · 0 courses · 0 providers

Training and certification in study instruments

Teaches the requirement for site personnel to be trained and certified on protocol-specific assessments, psychiatric instruments, rating scales, and study procedures before performing them in the trial.

3 roles · 3 guidelines · 0 courses · 0 providers

Trauma treatment background

Therapists need a solid professional background in psychotherapy, especially PTSD treatment. Prior experience with established trauma therapies and related approaches is considered important preparation for this work.

2 roles · 3 guidelines · 0 courses · 0 providers

TRD eligibility assessment

Understands and applies the protocol-defined criteria for treatment-resistant major depressive disorder, including diagnostic confirmation, episode severity, and prior treatment failure requirements. Must verify both current and historical antidepressant nonresponse and ensure the participant remains eligible at baseline.

2 roles · 3 guidelines · 0 courses · 0 providers

Understanding of trial procedures and schedule

Know the sequence, timing, and purpose of screening, preparation, dosing, scanning, follow-up, and unblinding visits. The therapist/facilitator must be able to work within the full protocol structure.

2 roles · 3 guidelines · 0 courses · 0 providers

Use clear, participant-centered communication

Therapists should communicate in language and nonverbal style the participant can readily follow, avoiding overly theoretical or confusing discourse.

2 roles · 3 guidelines · 0 courses · 0 providers

Virtual care facilitation

Capacity to conduct assessments and therapy sessions virtually when needed while preserving safety and confidentiality. The study permits telehealth sessions for certain visits and contingencies.

2 roles · 3 guidelines · 0 courses · 0 providers

Voluntary participation and non-coercion

The handbook explicitly states that the experience should be fully explained and that the subject should accept it voluntarily. Coercion is framed as both unethical and therapeutically counterproductive.

2 roles · 3 guidelines · 0 courses · 0 providers

Harm reduction and risk awareness

Cluster covering 5 related competencies including: Harm-reduction orientation, Harm reduction and risk awareness, Harm reduction for client support.

7 roles · 2 guidelines · 5 courses · 5 providers

Dosing-day facilitation

Cluster covering 2 related competencies including: Dosing-day facilitation, Dosing-session facilitation.

4 roles · 2 guidelines · 2 courses · 2 providers

Legal and Regulatory Navigation

Teaches practitioners to identify and apply relevant legal, regulatory, ethical, and institutional requirements, including documentation, consent, reporting, controlled-substance, and jurisdiction-specific obligations.

6 roles · 2 guidelines · 2 courses · 2 providers

Basic life support

Learners are explicitly offered Basic Life Support training, indicating emergency readiness and medical safety preparation. The page notes DORA-required status, signaling regulatory safety relevance.

5 roles · 2 guidelines · 1 courses · 1 providers

Facilitator self-awareness and self-care

The program includes facilitator development and self-care, and it explicitly calls on learners to recognize personal limitations and seek support. This suggests training in reflective practice and professional self-management.

3 roles · 2 guidelines · 1 courses · 1 providers

Action planning and relapse-prevention support

Helps participants convert motivation into specific behavior-change strategies. Uses structured planning tools and individualized modules to address triggers, coping, and alternative behaviors.

2 roles · 2 guidelines · 0 courses · 0 providers

Assess and engage support systems

Therapists should understand the participant’s support network and appropriately involve support persons when relevant and desired.

2 roles · 2 guidelines · 0 courses · 0 providers

Assessment of emotional stability after sessions

Therapists must remain with participants at the end of and immediately after experimental sessions until emotional stability is established. This requires real-time clinical judgment about readiness for reduced supervision.

4 roles · 2 guidelines · 0 courses · 0 providers

Assessment of indications and contraindications

The therapist must exercise clinical judgment about who may benefit, who may have difficulty surrendering defenses, and where evidence is limited. The handbook emphasizes uncertainty, need for research, and cautious selection based on insecurity, rigidity, suspicion, diagnosis, and treatment goals.

2 roles · 2 guidelines · 0 courses · 0 providers

Baseline history taking

Collect and interpret baseline behavioral, psychiatric, and medical history relevant to psilocybin research. This information is used to determine eligibility and contextualize outcomes.

2 roles · 2 guidelines · 0 courses · 0 providers

Ceremonial framing and intentional therapeutic setting

Facilitators require skill in establishing ceremonial and intentional framing around ketamine sessions to support therapeutic depth and coherence. This includes preparing participants for the significance and structure of the experience within the group model.

1 role · 2 guidelines · 0 courses · 0 providers

Clinical supervision participation

Engages in ongoing supervision and accepts feedback to maintain treatment quality. Supports corrective action when performance is unsatisfactory.

1 role · 2 guidelines · 0 courses · 0 providers

Clinical trial participant eligibility boundaries

Therapists must practice within the population and setting defined by the manual, limiting use to approved clinical trial subjects with PTSD. This boundary helps protect participants and preserves research integrity.

2 roles · 2 guidelines · 0 courses · 0 providers

Cognitive safety monitoring

Ability to monitor for short-term cognitive impairment following psychedelic administration. The study included tests designed to detect decrements in attention and processing speed.

2 roles · 2 guidelines · 0 courses · 0 providers

Collaboration with medical supervision

Therapists function within a medically supervised ketamine model and must coordinate closely with clinicians responsible for dosing oversight and safety clearance. This includes understanding role boundaries and supporting monitoring workflows.

3 roles · 2 guidelines · 0 courses · 0 providers

Competence in protocol adherence for dosing sessions

The intervention involved two separate psilocybin dosing sessions 3 weeks apart under a randomized controlled protocol, implying the need for facilitators to reliably support treatment according to a fixed schedule and study procedures.

2 roles · 2 guidelines · 0 courses · 0 providers

Coordinate with outside providers ethically

Therapists must coordinate with prescribing clinicians and existing psychotherapists when relevant, while respecting consent and confidentiality. Communication should support safety, continuity, and protocol integrity.

4 roles · 2 guidelines · 0 courses · 0 providers

Cultural and language competence for participation

Staff must ensure participants can understand and engage with the protocol in the site’s recognized language and can participate in a way that preserves safety and informed consent. This is part of the practical knowledge needed for ethical facilitation.

2 roles · 2 guidelines · 0 courses · 0 providers

Empathic presence and active listening

Therapists are expected to provide consistent empathic presence, nonjudgmental attunement, and deep listening throughout the process. This includes validating feelings, listening for deeper meaning, and creating psychological permission for openness.

2 roles · 2 guidelines · 0 courses · 0 providers

Ethical sourcing and ecological responsibility

The review explicitly discourages clinical development based on toad venom because of ethical and ecological concerns. Facilitators should favor synthetic sources and avoid practices that could harm wildlife or ecosystems.

2 roles · 2 guidelines · 0 courses · 0 providers

Function effectively as a therapy pair

Where co-therapy is used, therapists should work cohesively, remain present, and respect participant preferences within the dyad.

1 role · 2 guidelines · 0 courses · 0 providers

Laboratory safety monitoring

Review laboratory and biomarker data for clinically significant abnormalities, including chemistry, hematology, coagulation, and alcohol biomarkers. This supports medical safety surveillance during follow-up.

2 roles · 2 guidelines · 0 courses · 0 providers

Manage mandated reporting and safety concerns

Therapists/facilitators must fulfill professional legal duties and escalate safety or reporting concerns promptly.

2 roles · 2 guidelines · 0 courses · 0 providers

Management of assessment-related distress

Because interviews and questionnaires may provoke emotional reactions or fatigue, facilitators must respond supportively and mitigate burden. This includes addressing distress during assessments and offering breaks.

2 roles · 2 guidelines · 0 courses · 0 providers

Medication conversion and detoxification workflow

Coordinate the conversion from opioid maintenance treatment to morphine-sulphate prior to ibogaine dosing, reflecting the treatment sequence described in the study. This requires careful timing and clinical oversight.

2 roles · 2 guidelines · 0 courses · 0 providers

Monitor broad domains of well-being beyond symptom reduction

Safety monitoring in this context includes tracking not only adverse psychiatric states but also broader psychological, emotional, existential, and spiritual outcomes. Clinicians should watch for changes across multiple domains that may affect patient functioning and care needs.

1 role · 2 guidelines · 0 courses · 0 providers

Nasal tolerability assessment

Performs targeted nasal examinations and assesses local tolerability of esketamine nasal spray. Identifies findings that could affect drug delivery, safety, or continuation.

2 roles · 2 guidelines · 0 courses · 0 providers

Nausea and vomiting management

Recognize and respond to gastrointestinal adverse effects that may occur frequently with higher doses. Manage emesis to reduce aspiration risk, dehydration, and treatment disruption.

2 roles · 2 guidelines · 0 courses · 0 providers

Nighttime and overnight participant support

When overnight stays are required, facilitators and attendants must maintain safe observation and supportive presence without acting as outside therapists. They need to monitor comfort, safety, and emergency access overnight.

2 roles · 2 guidelines · 0 courses · 0 providers

Non-directive facilitation

Therapists must facilitate rather than control the participant's process, using invitations and timing interventions carefully. They should preserve the participant-led unfolding of experience while knowing when gentle direction or safety-based assertiveness is needed.

2 roles · 2 guidelines · 0 courses · 0 providers

Non-responder handoff and continuity of care

The facilitator must ensure non-responders are transitioned safely back to clinical care. Continuity of care is explicitly required to support ongoing psychiatric treatment.

2 roles · 2 guidelines · 0 courses · 0 providers

Optional biomarker/genomic research handling

Understands the optional nature and operational limits of biomarker and pharmacogenomic collection. Ensures consent, timing, fasting guidance, and sample handling requirements are respected.

2 roles · 2 guidelines · 0 courses · 0 providers

Outcome and safety measure literacy

Knowledge of the trial’s primary, secondary, and exploratory endpoints and the instruments used to assess them. This enables accurate administration and interpretation of study procedures.

2 roles · 2 guidelines · 0 courses · 0 providers

Patient monitoring during ibogaine administration

Monitors patients closely during treatment because serious adverse outcomes may occur. Safety monitoring is essential given that one participant died during treatment in the study.

2 roles · 2 guidelines · 0 courses · 0 providers

Pharmacokinetic awareness

Understands the drug’s rapid absorption profile and lack of accumulation with repeated dosing. Uses this knowledge to anticipate timing of effects and safety observations.

2 roles · 2 guidelines · 0 courses · 0 providers

Professional qualification and supervised practice

Lead therapists must hold appropriate licensure and regulatory registration to provide psychotherapy, and have prior PAP experience. Unlicensed or inexperienced therapists may participate only under direct supervision.

4 roles · 2 guidelines · 0 courses · 0 providers

Protection against coercion and dual-role influence

The protocol explicitly addresses the risk of undue influence when investigators recruit current or former patients, requiring safeguards and ongoing monitoring for coercion.

2 roles · 2 guidelines · 0 courses · 0 providers

Protocol adherence and visit scheduling

Ability to manage the study schedule, windows, and follow-up procedures accurately. This supports treatment delivery and valid outcome collection.

2 roles · 2 guidelines · 0 courses · 0 providers

Relapse prevention psychotherapy delivery

Deliver ongoing relapse prevention psychotherapy after dosing through the post-dose follow-up period. The approach is used to support alcohol recovery and translate treatment effects into behavior change.

1 role · 2 guidelines · 0 courses · 0 providers

Respiratory monitoring

Facilitators must watch for slowed breathing, sleep apnea-related hypoxia, disordered breathing, and oxygen desaturation. Oxygenation needs ongoing assessment during the acute and post-acute periods.

2 roles · 2 guidelines · 0 courses · 0 providers

Retention and engagement skills

Given the risk of high attrition, facilitators need strong engagement and follow-up skills. The protocol explicitly notes the importance of respecting time commitments, tracking procedures, and strong interpersonal skills of study personnel.

1 role · 2 guidelines · 0 courses · 0 providers

Risk-benefit judgment

Balances potential symptom relief against known and emerging safety risks in participants with opioid dependence. Makes conservative decisions when cardiac or adverse-effect concerns outweigh anticipated benefit.

2 roles · 2 guidelines · 0 courses · 0 providers

Safety monitoring for adverse effects

Monitors for potential adverse effects associated with ibogaine administration and the detoxification period, even though the abstract primarily reports outcomes rather than specific events.

2 roles · 2 guidelines · 0 courses · 0 providers

Safety oversight and independent review

Clinical investigators must work within independent safety monitoring structures and avoid conflicts in oversight roles. Therapists/facilitators in research settings should support scheduled review of participant safety outcomes.

2 roles · 2 guidelines · 0 courses · 0 providers

Shared decision-making and referral coordination

Collaborates with patients, medical practitioners, and referring providers to support individualized care. Helps patients consider alternatives and coordinate ongoing treatment needs.

3 roles · 2 guidelines · 0 courses · 0 providers

Stress inoculation and breathwork instruction

At least one therapist must be able to teach stress inoculation methods, especially diaphragmatic breathing, and apply breath-based interventions during sessions. Breath is used both for relaxation and for staying present with difficult experience.

2 roles · 2 guidelines · 0 courses · 0 providers

Track cognitive performance during treatment

Because cognitive performance during treatment is a named secondary outcome, clinicians involved in care should be able to monitor and document cognitive functioning relevant to treatment participation. This supports safety oversight and interpretation of treatment effects.

2 roles · 2 guidelines · 0 courses · 0 providers

Training in PAP and protocol manual adherence

Therapists must be specifically trained in psilocybin-assisted psychotherapy and in the study’s manualized procedures. Competence includes familiarity with the therapeutic model and difficult-state management guidance.

2 roles · 2 guidelines · 0 courses · 0 providers

Use of structured clinical and psychological measures

Therapists/facilitators should know the main assessment domains used in KPT research and clinical monitoring, including craving, depression, anxiety, anhedonia, addiction severity, and purpose in life. This knowledge supports case formulation and tracking change.

2 roles · 2 guidelines · 0 courses · 0 providers

Video review and supervision participation

Work within a supervised treatment model that includes review of recorded sessions and feedback. The facilitator must accept supervision, use feedback constructively, and support fidelity reviews.

3 roles · 2 guidelines · 0 courses · 0 providers

Withdrawal symptom assessment

Measure opioid withdrawal severity using standardized instruments and interpret symptom severity over time. Facilitators must be able to collect both objective observation and patient-reported data.

2 roles · 2 guidelines · 0 courses · 0 providers

Work within medically supervised settings

LSD-assisted psychotherapy in this study is explicitly framed as medically supervised. Therapists/facilitators need to practice within a setting capable of medical oversight and management of prolonged altered states.

4 roles · 2 guidelines · 0 courses · 0 providers

Working with family/collateral supports

The protocol expects involvement of relatives in follow-up, indicating a facilitator competency in engaging collateral supports. This helps verify outcomes and sustain recovery monitoring.

2 roles · 2 guidelines · 0 courses · 0 providers

Psychedelic research literacy and evidence appraisal

Teaches how to interpret the psychedelic clinical evidence base, compare strength of evidence across indications, understand mechanism theories, and critically appraise research claims. The competency supports evidence-informed practice rather than relying on general field narratives.

7 roles · 1 guidelines · 11 courses · 8 providers

Trauma-informed care

Cluster covering 2 related competencies including: Trauma-informed care, Trauma-informed psychedelic care.

4 roles · 1 guidelines · 4 courses · 4 providers

Professional Scope and Practice Alignment

Teaches clinicians to recognise their role boundaries, align services with training, licensure, supervision, and organisational policy, and refer or escalate when participant needs fall outside their scope of competence.

6 roles · 1 guidelines · 3 courses · 2 providers

Pharmacology, contraindications, and interaction awareness

Teaches psychoactive substance pharmacology, expected drug effects, contraindications, and relevant drug-interaction risks. The competency supports safer screening, medication review, participant education, and clinical decision-making.

6 roles · 1 guidelines · 2 courses · 2 providers

Psychedelic harm reduction and integration fundamentals

Cluster covering 2 related competencies including: Psychedelic harm reduction and integration therapy, Psychedelic harm reduction and integration fundamentals.

5 roles · 1 guidelines · 2 courses · 1 providers

Trauma-informed practice

Cluster covering 2 related competencies including: Trauma-informed practice, Trauma-informed clinical practice.

2 roles · 1 guidelines · 2 courses · 1 providers

Active listening micro-skills

Therapists are expected to use concrete active listening skills that support exploration without overdirecting. These communication skills help maintain emotional safety and participant agency.

2 roles · 1 guidelines · 0 courses · 0 providers

Acute monitoring of subjective intensity

Track the participant’s subjective drug intensity during the active phase of the session. This includes recognizing when the participant cannot respond and how to document maximum intensity.

2 roles · 1 guidelines · 0 courses · 0 providers

Aftercare planning

Develop follow-up care after the acute ibogaine period to support behavior change and relapse prevention. The manual emphasizes that the treatment session alone is not enough for long-term recovery.

1 role · 1 guidelines · 0 courses · 0 providers

Alcohol abstinence screening and enforcement

Ensure required abstinence conditions are met before dosing and make clinical judgments about rescheduling or exclusion when they are not. This protects safety and protocol integrity.

2 roles · 1 guidelines · 0 courses · 0 providers

Alcohol use disorder clinical knowledge

Have a working understanding of moderate to severe AUD, relapse processes, craving, withdrawal, and common comorbidities. This knowledge is required to deliver the integrated treatment model safely and effectively.

2 roles · 1 guidelines · 0 courses · 0 providers

Alcohol withdrawal risk management

Clinicians must recognize the life-threatening nature of alcohol withdrawal and ensure adequate detoxification before treatment. Postponement and medical supervision are required when withdrawal risk is present.

1 role · 1 guidelines · 0 courses · 0 providers

Assess and prepare social support

Therapists should evaluate the participant’s support network and help plan how supports can assist between sessions. They must also guide participants about the benefits and risks of disclosing their experiences to others.

2 roles · 1 guidelines · 0 courses · 0 providers

Assess psychosocial functioning

Competent delivery includes monitoring psychosocial functioning in addition to depressive symptoms. The source reports psychosocial functioning as a treatment outcome sustained through follow-up.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment administration and sequencing

Administer study assessments in the correct order and in the correct format. The protocol depends on reliable, standardized administration by trained site personnel and central raters.

1 role · 1 guidelines · 0 courses · 0 providers

Assessment of existential distress and mood symptoms

Administer and interpret the study's psychosocial measures relevant to existential distress, depression, spiritual well-being, and death-related distress. These assessments are used for screening and outcome monitoring.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment of psychological readiness and vulnerability

Before administration, facilitators should assess readiness and factors that could increase the chance of a difficult session. The source highlights that preoccupation, rigidity, low trust, and poor support can worsen experiences.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment of treatment effectiveness

Ability to contribute to evaluation of the effectiveness of LSD-assisted psychotherapy. The study is explicitly described as investigating safety and effectiveness.

1 role · 1 guidelines · 0 courses · 0 providers

Assessment of treatment response

Track onset, duration, and phases of ibogaine effects as part of clinical monitoring. The manual describes multiple stages of effect and expects the provider to observe them carefully.

2 roles · 1 guidelines · 0 courses · 0 providers

Assessment-related participant support

Therapists and study staff must manage participant distress and fatigue associated with questionnaires and interviews. Competence includes pacing, offering breaks, and responding supportively to emotionally evocative content.

2 roles · 1 guidelines · 0 courses · 0 providers

Ataxia and neurologic monitoring

Assess for cerebellar adverse effects such as ataxia during and after ibogaine administration. The source indicates ataxia is likely driven by ibogaine exposure and should be tracked systematically.

2 roles · 1 guidelines · 0 courses · 0 providers

Awareness of ibogaine pharmacology and effects

Understand the proposed mechanisms, phases of effect, and common subjective and physical effects of ibogaine relevant to clinical supervision. This knowledge informs safe monitoring and therapeutic pacing.

2 roles · 1 guidelines · 0 courses · 0 providers

Awareness of interaction and formulation cautions

The therapist/facilitator must understand potential drug-interaction concerns and formulation-related differences that could alter tolerability or safety. The source mentions caution with antiemetics and alternative preparations.

2 roles · 1 guidelines · 0 courses · 0 providers

Ayahuasca pharmacology and dosing awareness

Facilitators need basic knowledge of ayahuasca composition, dosing, and interaction risks to support safe administration. The protocol emphasizes dose calculation, substance composition, and monitoring for contraindications.

1 role · 1 guidelines · 0 courses · 0 providers

Benzodiazepine-support management

Use supportive anxiolytic or hypnotic medication only when allowed and clinically indicated. This requires careful judgment to balance comfort, safety, and preservation of the session’s integrity.

2 roles · 1 guidelines · 0 courses · 0 providers

Boundary-respecting physical support

Use physical contact only when necessary, explicitly permitted, and minimal. The facilitator must respect participant autonomy and avoid any contact that is not justified for safety or grounding.

1 role · 1 guidelines · 0 courses · 0 providers

Boundary-setting around external supports and media

Therapists must help participants manage disclosure, social support, and media contact carefully to protect privacy and emotional safety. They should advise discretion without controlling the participant's choices.

1 role · 1 guidelines · 0 courses · 0 providers

Candidate selection and risk-benefit assessment

Evaluate whether a person is an appropriate candidate for ibogaine treatment by balancing potential benefit against medical risk. This includes identifying treatment-refractory opioid use disorder and weighing cardiotoxicity and other safety concerns against the harms of untreated substance use disorder.

2 roles · 1 guidelines · 0 courses · 0 providers

Cardiac safety and QT monitoring

Understands and monitors concentration-related cardiac risk, especially QTc prolongation, in participants receiving noribogaine or similar agents. Uses ECG findings to support safe trial conduct and participant protection.

2 roles · 1 guidelines · 0 courses · 0 providers

Cardiac safety awareness

The study specifically reports no QT prolongation, indicating that cardiac safety was an important monitoring domain. Facilitators must be aware of relevant safety surveillance and the need to identify concerning effects.

1 role · 1 guidelines · 0 courses · 0 providers

Cardiovascular safety screening

Screen for cardiovascular risk before treatment because ibogaine may prolong the QT interval and has been linked to arrhythmias and deaths. Exclude or carefully manage patients with cardiac disease and other risk factors.

2 roles · 1 guidelines · 0 courses · 0 providers

CBT expertise for mood disorders

Clinicians must have working expertise in evidence-based CBT for depression and related mood conditions, including the ability to deliver core CBT components across preparation, post-session integration, and relapse prevention phases. The protocol assumes competence in standard CBT delivery as the psychosocial backbone of treatment.

2 roles · 1 guidelines · 0 courses · 0 providers

Clinical experience for assistant facilitator

Assistant facilitators require practical clinical experience in a licensed healthcare setting. Their role supports safety, containment, and session logistics rather than independent psychotherapy practice.

1 role · 1 guidelines · 0 courses · 0 providers

Clinical judgment for exclusion of high-risk patients

Exclude or defer patients whose medical risk is too high, especially those with cardiovascular disease or other major contraindications. This is central to safer administration according to the source.

2 roles · 1 guidelines · 0 courses · 0 providers

Clinician therapist availability and scope

At least one therapist in the dyad must be a clinician with capability to assess and manage medical or psychiatric adverse events during the dosing session. This reflects a required competency boundary between general support and clinical responsibility.

2 roles · 1 guidelines · 0 courses · 0 providers

Cognitive-behavioral smoking cessation counseling

Deliver structured CBT-based smoking cessation support throughout the trial. Facilitators teach practical self-management strategies before and after the target quit date.

2 roles · 1 guidelines · 0 courses · 0 providers

Collaboration with medical and nursing staff

Ketamine-assisted treatment in this protocol is multidisciplinary, so facilitators must work closely with study doctors and nurses. This includes coordinating preparation, understanding monitoring responsibilities, and escalating concerns appropriately.

1 role · 1 guidelines · 0 courses · 0 providers

Combination risk awareness

Facilitators must know that combining 5-MeO-DMT with other psychoactives or MAO-inhibitors can be dangerous or fatal. Careful pacing and separation from other substances are necessary.

2 roles · 1 guidelines · 0 courses · 0 providers

Communicate risks, benefits, and alternatives

The investigator/therapist has ethical responsibility to explain study goals, course, expected effects, possible advantages and disadvantages, risks, and alternative treatments in verbal and written form. This includes ensuring participant questions are answered satisfactorily and that there is enough time for decision-making.

1 role · 1 guidelines · 0 courses · 0 providers

Community network and sustainability building

Responsible practitioners cultivate relationships with other practitioners and community networks to support sustainable care. They help build systems that expand access while preserving integrity and safety.

2 roles · 1 guidelines · 0 courses · 0 providers

Competence with open-label continuation procedures

Understand the transition from blinded randomized treatment to open-label MDMA-assisted therapy for eligible participants. This includes separate consent, revised scheduling, and altered assessment timing.

1 role · 1 guidelines · 0 courses · 0 providers

Contextualization and ceremony design

Facilitators may use ritual, music, prayer, altar work, or minimalist approaches to frame the experience. Whatever the style, they should use contextualization intentionally and in service of the participant’s process.

2 roles · 1 guidelines · 0 courses · 0 providers

Continuous physical monitoring

Participants must be continuously monitored to prevent avoidable hazards. The guide explicitly states that participants should never be left alone.

2 roles · 1 guidelines · 0 courses · 0 providers

COVID-19 infection control

Implement infection-prevention procedures during in-person study and dosing visits. Facilitators must screen participants, use PPE, maintain distancing when feasible, and adapt procedures based on test results or symptoms.

2 roles · 1 guidelines · 0 courses · 0 providers

Delegation and escalation

Facilitators should know when and how to ask for help and delegate tasks. This is essential in emergencies and difficult situations.

2 roles · 1 guidelines · 0 courses · 0 providers

Detect and address unethical attitudes or behaviors

Trainers and mentors observe therapists for conduct that could place participants at risk. Therapists must be receptive to correction and able to modify problematic behavior or seek additional training.

2 roles · 1 guidelines · 0 courses · 0 providers

Deterioration triage and referral

Ability to judge clinical worsening over time and determine whether a participant can remain in the study or requires higher-level care. This is a continuing monitoring responsibility throughout the trial.

1 role · 1 guidelines · 0 courses · 0 providers

Device deficiency and product quality complaint handling

Identifies and reports device deficiencies and product quality complaints related to the nasal spray device or product packaging. Ensures immediate escalation when malfunctions or labeling issues occur.

2 roles · 1 guidelines · 0 courses · 0 providers

Documentation and note-taking

Document participant experiences and relevant observations to support continuity, recall, and study integrity. Notes may also serve as a participant memory aid after dosing sessions.

2 roles · 1 guidelines · 0 courses · 0 providers

Documentation of subjective experience

The therapist/facilitator must record participant-reported effects and clinically relevant observations accurately. Documentation supports both safety monitoring and outcome interpretation.

2 roles · 1 guidelines · 0 courses · 0 providers

Eating disorder clinical knowledge

Knowledge of anorexia nervosa symptomatology, risk, and clinical instability relevant to screening and treatment monitoring. The study requires awareness of eating-disorder-specific risks and outcomes.

2 roles · 1 guidelines · 0 courses · 0 providers

Electrolyte and medical screening

Assess for physiologic factors that may increase ibogaine-related harm, especially electrolyte abnormalities. The source identifies electrolyte screening as part of safer administration.

2 roles · 1 guidelines · 0 courses · 0 providers

Emergency medication knowledge

Knows the purpose and indications of medications maintained for side effect management or emergency use during KAP. Can explain how these medications relate to specific risks.

2 roles · 1 guidelines · 0 courses · 0 providers

Emergency planning

A clear emergency plan is required before the session begins. The whole team must understand what to do in various scenarios.

2 roles · 1 guidelines · 0 courses · 0 providers

Emergency response readiness

Be prepared to recognize medical deterioration and summon emergency help immediately. The manual states that providers who cannot call for emergency assistance should not provide ibogaine therapy.

1 role · 1 guidelines · 0 courses · 0 providers

Escitalopram monitoring and counseling

Understand the common and serious adverse effects, interaction risks, and monitoring needs of escitalopram. This includes cardiac, psychiatric, sexual, and withdrawal-related concerns.

2 roles · 1 guidelines · 0 courses · 0 providers

Ethical risk communication

Communicates the experimental and unregulated nature of ibogaine treatment honestly. The source highlights an ibogaine subculture offering unregulated preparations, which creates an ethical duty to disclose uncertainty and risks.

2 roles · 1 guidelines · 0 courses · 0 providers

Ethical supervision in experimental drug administration

Ensure that administration occurs within an ethically supervised research or clinical framework with informed oversight and careful risk-benefit consideration. Hallucinogenic agents require especially cautious use in vulnerable psychiatric populations.

1 role · 1 guidelines · 0 courses · 0 providers

Ethical use of nonstandard interventions

Uses a cautious, transparent ethical approach when working with an experimental or non-approved addiction treatment context.

2 roles · 1 guidelines · 0 courses · 0 providers

Ethical use of reassurance

Provide reassurance when it helps establish safety, while avoiding invalidation or minimization. Reassurance should support rather than dismiss the patient’s experience.

2 roles · 1 guidelines · 0 courses · 0 providers

Evaluate readiness and contraindications for subsequent sessions

After each MDMA session, therapists must assess whether continuing treatment is safe and clinically appropriate. The participant’s choice is respected unless safety concerns warrant exclusion.

1 role · 1 guidelines · 0 courses · 0 providers

Family or companion safety education

Therapists/facilitators should be able to educate companions about clinical warning signs and how to contact the study team. This extends monitoring beyond the clinic and supports rapid response to deterioration.

2 roles · 1 guidelines · 0 courses · 0 providers

Group facilitation and relational process leadership

Therapists and facilitators must be able to guide intentional group process in a way that supports safety, connection, and meaningful change. This includes managing both large- and small-group formats and maintaining a relationally anchored therapeutic environment.

2 roles · 1 guidelines · 0 courses · 0 providers

Group risk escalation

Responds appropriately to safety threats disclosed in group therapy. Follows up on suicide, homicide, abuse, or neglect concerns and escalates when necessary.

2 roles · 1 guidelines · 0 courses · 0 providers

Hydration and electrolyte management

Providers must maintain hydration and avoid electrolyte depletion because dehydration and electrolyte abnormalities increase cardiac risk. Hydration is to be monitored before, during, and after treatment.

2 roles · 1 guidelines · 0 courses · 0 providers

Hydration management

Prevent dehydration during and after ibogaine treatment. The manual stresses that patients may not feel like drinking and that dehydration can become dangerous, especially if vomiting occurs.

2 roles · 1 guidelines · 0 courses · 0 providers

Ibogaine-specific cardiac vigilance

Understand the unique cardiovascular hazards associated with ibogaine and the need for intensive cardiac oversight. The facilitator should know that cardiac risk is a central safety issue rather than a minor side effect.

3 roles · 1 guidelines · 0 courses · 0 providers

Identify early improvement and dropout risk during PE

The study examines whether early improvement during PE relates to dropout rates, implying a competency in recognizing early response patterns and engagement risk. Therapists should monitor participation closely and intervene to support retention when possible.

1 role · 1 guidelines · 0 courses · 0 providers

Imaging and procedure-related awareness

Understands the implications of PET, MRI, blood sampling, and TMS-EEG procedures for participant comfort and safety. While not necessarily performing these procedures, the therapist/facilitator should know their risks and scheduling constraints.

2 roles · 1 guidelines · 0 courses · 0 providers

Inclusivity and non-discrimination in participant engagement

Therapist/facilitator practice in the study must align with equity, diversity, and inclusion commitments by avoiding exclusions based on protected or social identity characteristics outside protocol-defined scientific/safety criteria. This supports ethically sound participant engagement.

2 roles · 1 guidelines · 0 courses · 0 providers

Inform participants of new safety-relevant findings

Investigators have a continuing duty to inform participants about new findings regarding LSD or LSD-assisted therapy that emerge during the study. This reflects an ongoing consent responsibility rather than a one-time disclosure.

1 role · 1 guidelines · 0 courses · 0 providers

Informed consent and ethical use in uncertain evidence

Use ibogaine only after a careful discussion of uncertain efficacy, limited research, and known risks. Ethical practice requires transparent communication about the experimental nature of treatment and the absence of robust clinical standards.

2 roles · 1 guidelines · 0 courses · 0 providers

Informed consent and experimental-treatment disclosure

Clearly explain the investigational nature of ibogaine treatment and its known serious risks before treatment begins. Ethical practice requires that patients understand both uncertain benefits and significant safety concerns.

2 roles · 1 guidelines · 0 courses · 0 providers

Informed consent boundary awareness

Study personnel involved with participants must understand informed consent responsibilities and boundaries. Consent is an ongoing process, and appropriately trained staff without an existing clinical relationship obtain consent, not the PI.

2 roles · 1 guidelines · 0 courses · 0 providers

Informed oversight for vulnerable participants

Exercises heightened ethical responsibility when working with people with opioid dependence undergoing medication changes. Ensures participation remains voluntary, monitored, and clinically appropriate.

1 role · 1 guidelines · 0 courses · 0 providers

Integrate support persons appropriately

Therapists must work thoughtfully with the patient's social support system to enhance safety and continuity of care. This includes selective disclosure, education, involvement in sessions when appropriate, and crisis planning.

1 role · 1 guidelines · 0 courses · 0 providers

Interprofessional coordination and referral management

Safe delivery requires coordination among therapists, physicians, nurses, blinded assessors, outside therapists, and emergency services.

2 roles · 1 guidelines · 0 courses · 0 providers

Knowledge of psilocybin and antidepressant treatment context

Facilitators should understand the therapeutic and adverse-effect context of psilocybin and comparator antidepressant treatment, since the trial directly compared psilocybin with escitalopram.

1 role · 1 guidelines · 0 courses · 0 providers

Knowledge of psychedelic session structure

Facilitators need to understand the full treatment sequence and how each phase contributes to safety and treatment delivery. The intervention depends on correct sequencing and timing.

2 roles · 1 guidelines · 0 courses · 0 providers

Knowledge of risks and benefits of MDMA-assisted therapy

Clinicians need working knowledge of the potential risks and benefits of MDMA-assisted therapy as the research is designed to explore both. This knowledge supports informed consent, clinical judgment, and participant monitoring.

1 role · 1 guidelines · 0 courses · 0 providers

Knowledge of target population risks and context

Therapists need specific knowledge of methamphetamine use disorder, HIV risk behaviors, and the social context of affected populations to deliver relevant and responsive care. This includes understanding how methamphetamine use intersects with trauma, sexual risk, and HIV prevention or treatment adherence.

2 roles · 1 guidelines · 0 courses · 0 providers

Knowledge of therapeutic mechanism and expected time course

The therapist/facilitator should know the expected onset, peak, and persistence of effects to guide monitoring and interpretation. The source reports acute effects with follow-up improvements lasting days.

2 roles · 1 guidelines · 0 courses · 0 providers

Knowledge of toxicity profile and cardiac risk

Understand that ibogaine has a significant toxicity profile, especially cardiotoxicity. Fatalities have been temporally associated with use, often in the setting of medical comorbidity, co-use, or electrolyte imbalance.

2 roles · 1 guidelines · 0 courses · 0 providers

Laboratory interpretation

Order, review, and interpret core laboratory studies relevant to ibogaine safety and metabolism. Competence includes recognizing abnormal values that increase risk or signal exclusion from treatment.

2 roles · 1 guidelines · 0 courses · 0 providers

Legal awareness

Those organizing sessions should understand the legal implications of ayahuasca in their jurisdiction. This helps them manage accountability and reduce legal risk.

2 roles · 1 guidelines · 0 courses · 0 providers

Limits of confidentiality disclosure

Explains the boundaries of confidentiality so patients understand when information may be disclosed without permission. Applies legal and ethical duties related to safety, abuse, and mandated reporting.

2 roles · 1 guidelines · 0 courses · 0 providers

Lost-to-follow-up procedures

The facilitator must make repeated documented efforts to contact participants who miss visits. Follow-up processes differ for responders and non-responders.

1 role · 1 guidelines · 0 courses · 0 providers

Maintain a post-session safety net

Therapists must provide continuity, availability, and clear support structures after MDMA sessions to reduce anxiety and manage emerging difficulties. This safety net extends beyond the dosing day.

2 roles · 1 guidelines · 0 courses · 0 providers

Management of acute confusional state

Providers must be able to recognize and safely manage acute confusional states, which may look like a psychological break from reality. The emphasis is on physical safety, constant supervision, and avoiding abrupt antipsychotic intervention.

1 role · 1 guidelines · 0 courses · 0 providers

Management of comorbidities

Facilitators need competence in working with PTSD when comorbid conditions are present. The source explicitly notes dissociation, depression, alcohol/substance use disorders, and childhood trauma.

1 role · 1 guidelines · 0 courses · 0 providers

Management of hypertension and cardiovascular complications

Therapists in this setting must recognize abnormal cardiovascular responses and follow protocolized responses for hypertensive crisis, angina, myocardial infarction, or stroke.

2 roles · 1 guidelines · 0 courses · 0 providers

Management of treatment-induced complications

Respond promptly to complications arising during ibogaine-supported detoxification. Facilitators need a clear escalation plan for QTc prolongation and intolerable withdrawal.

1 role · 1 guidelines · 0 courses · 0 providers

Managing short-duration high-intensity sessions

5-MeO-DMT produces a very short but intense experience, which changes facilitation demands. Facilitators must be prepared for rapid transitions into and out of the altered state.

1 role · 1 guidelines · 0 courses · 0 providers

Medical contraindication screening

Recognizes medical factors that may increase risk during inhaled 5-MeO-DMT administration. Medical clearance is required before dosing.

2 roles · 1 guidelines · 0 courses · 0 providers

Medical symptom monitoring and selective testing

Therapists/facilitators must monitor for adverse medical signs during sessions and obtain targeted testing when clinically indicated. Safety practice should balance participant comfort with symptom-triggered medical evaluation.

2 roles · 1 guidelines · 0 courses · 0 providers

Medication interaction screening

Screen for co-medications that may prolong QTc or affect CYP2D6 metabolism. This is critical to reduce confounding and prevent additive toxicity.

2 roles · 1 guidelines · 0 courses · 0 providers

Medication reconciliation and interaction management

Therapists must understand clinically significant drug interactions with ibogaine, including QT-prolonging, serotonergic, centrally acting, and CYP2D6-related medications. This knowledge informs screening, tapering, and dosing decisions.

2 roles · 1 guidelines · 0 courses · 0 providers

Monitor symptom outcomes beyond PTSD

The protocol includes secondary outcomes for depression and anxiety severity, so clinicians should be able to assess and track these domains alongside PTSD symptoms. This broadens case monitoring and supports comprehensive clinical oversight.

2 roles · 1 guidelines · 0 courses · 0 providers

Monitoring and documentation of device-related issues

Because study drug delivery uses a vaporization device, staff must be able to recognize, document, and escalate device deficiencies. Device issues may have safety implications even when no patient harm occurs.

2 roles · 1 guidelines · 0 courses · 0 providers

Monitoring depressive aftermath and unmet integration

The therapist should watch for depression after the experience, particularly when insights are not translated into action. Continued support is presented as a way to reduce this risk and restore constructive orientation.

1 role · 1 guidelines · 0 courses · 0 providers

Monitoring psychological defenses and change processes

Ability to observe and interpret defense mechanisms and other psychological processes during therapy. This is implied by the MeSH term 'Defense Mechanisms' and psychotherapy context.

1 role · 1 guidelines · 0 courses · 0 providers

Music selection and management

Use music intentionally as part of the therapeutic environment and processing sequence. Music should support, not direct, the patient’s unfolding internal experience.

1 role · 1 guidelines · 0 courses · 0 providers

Nasal administration awareness

Understand the intranasal administration procedure and related local adverse effects. The facilitator must support safe delivery and monitor nasal reactions.

1 role · 1 guidelines · 0 courses · 0 providers

Neurologic adverse effect monitoring

Monitor for cerebellar toxicity and gait disturbance because severe transient ataxia was observed in all patients in the study. The facilitator must be able to detect impaired coordination and prevent falls or injury.

1 role · 1 guidelines · 0 courses · 0 providers

Non-leading symptom inquiry

Ask about symptoms and adverse effects in a neutral, non-suggestive manner. This reduces bias and improves safety detection in a vulnerable oncology population.

2 roles · 1 guidelines · 0 courses · 0 providers

Non-restrictive physical protection

Facilitators must protect participants and others from harm without unnecessarily restraining the participant. The guidance emphasizes containing danger rather than restraining movement.

2 roles · 1 guidelines · 0 courses · 0 providers

On-site physician emergency competence

A study physician with psychiatric and cardiovascular emergency expertise must be available during dosing. This reflects a requirement for advanced emergency readiness and clinical judgment.

1 role · 1 guidelines · 0 courses · 0 providers

Ongoing informed consent

Treat consent as a continuing process rather than a one-time event. Patients must understand the treatment and retain the ability to revoke consent, with special procedures during the medication session for safety.

2 roles · 1 guidelines · 0 courses · 0 providers

Operational prioritization of assessments

Sequences study procedures correctly to reduce bias and protect participant safety. Particularly prioritizes PROs, clinician ratings, and dosing-day procedures in the required order.

2 roles · 1 guidelines · 0 courses · 0 providers

Outcome interpretation in pilot research settings

Understands that findings from a pilot evaluation support feasibility and preliminary effectiveness rather than definitive efficacy. The facilitator should interpret outcomes cautiously and support structured data collection.

1 role · 1 guidelines · 0 courses · 0 providers

Overdose, misuse, and abuse-liability vigilance

Facilitators are expected to monitor for signs of misuse, diversion, dependence, or other abuse-related phenomena even though the medication is administered only on-site. They must also recognize protocol violations or dropout patterns that may signal abuse liability concerns.

1 role · 1 guidelines · 0 courses · 0 providers

Participant safety awareness

Maintains awareness that any clinical trial context may involve participant risk and requires appropriate safeguards. Even minimal source text implies the need for cautious, non-assumptive practice.

2 roles · 1 guidelines · 0 courses · 0 providers

Participant transition and stabilization awareness

Understands the clinical context of switching participants from methadone to morphine before study participation. Appreciates how opioid substitution transitions can affect symptom interpretation and safety monitoring.

1 role · 1 guidelines · 0 courses · 0 providers

Patient selection and risk awareness

Applies cautious patient selection when considering ibogaine for opioid detoxification, particularly for individuals with refractory opioid use disorder.

2 roles · 1 guidelines · 0 courses · 0 providers

Pharmacokinetic literacy

Understands core pharmacokinetic concepts needed to interpret study findings and guide safety observation. Recognizes dose-linear exposure changes and elimination characteristics relevant to monitoring windows.

2 roles · 1 guidelines · 0 courses · 0 providers

Pre-onset psychological set management

Before symptoms begin, the therapist must prevent boredom, over-monitoring for effects, and escalating apprehension. This phase is treated as crucial because the psychological set established here shapes much of what follows.

1 role · 1 guidelines · 0 courses · 0 providers

Pre-session medical screening

The therapist/facilitator must ensure medical suitability before ayahuasca administration by checking for conditions that increase risk. Screening should include physical exam, laboratory testing, and pregnancy assessment when indicated.

2 roles · 1 guidelines · 0 courses · 0 providers

Preparation for ketamine sessions

Therapists must prepare participants psychologically and practically for ketamine dosing through rapport-building, psychoeducation, expectation-setting, and intention development. Preparation is emphasized because of trauma burden, psychiatric comorbidity, and instability in the target population.

1 role · 1 guidelines · 0 courses · 0 providers

Product identity verification

Verify the formulation and potency of the ibogaine product before administration. The manual warns that confusion between HCl, extract, and root bark can cause underdosing or fatal overdosing.

2 roles · 1 guidelines · 0 courses · 0 providers

Professional ethics and policy adherence

Adheres to organizational code of ethics, privacy policy, electronic communication policy, and applicable laws. Maintains professional conduct across contractor and clinic arrangements.

2 roles · 1 guidelines · 0 courses · 0 providers

Professional training in human subjects research

Expectation that study personnel are trained in research ethics and responsible conduct of research. This underpins appropriate consent, confidentiality, and participant safety practices.

2 roles · 1 guidelines · 0 courses · 0 providers

Protocol adherence and dose conditions

Follows the study's operational rules for dose timing, progression, and stopping conditions. Reliable execution is necessary for both safety and interpretability of results.

2 roles · 1 guidelines · 0 courses · 0 providers

Provide protocol-consistent patient education and informed framing

Clinicians should present the intervention accurately as ketamine- or midazolam-augmented PE within a research protocol, with clear explanation of purpose and expectations. Ethical practice includes avoiding overstatement of benefit and framing treatment as investigational augmentation of an established therapy.

1 role · 1 guidelines · 0 courses · 0 providers

Psychedelic pharmacology and interaction awareness

Understand the pharmacology and interaction risks of 5-MeO-DMT/BPL-003, including serotonergic and cardiovascular concerns. This knowledge informs safe preparation, exclusion screening, and monitoring.

2 roles · 1 guidelines · 0 courses · 0 providers

Reactivation event assessment

Identify and document possible post-dose reactivation or flashback-like experiences. The therapist must capture timing, context, emotional valence, and functional impact of these events.

1 role · 1 guidelines · 0 courses · 0 providers

Recognition of contextual limitations

The facilitator should understand that effects observed in a controlled clinical setting may differ from those in ceremonial or ritual contexts. This awareness shapes interpretation and informs safer translation to other settings.

2 roles · 1 guidelines · 0 courses · 0 providers

Recognition of contraindications and medication interactions

Facilitators need knowledge of conditions and medications that may make 5-MeO-DMT unsafe or inappropriate. They should identify possible interactions and discuss them clearly before participation.

2 roles · 1 guidelines · 0 courses · 0 providers

Recognize and support vulnerability under altered states

Because participants may be more suggestible during psychedelic sessions, therapists must actively protect against manipulation and unsafe influence. This requires vigilance and careful conduct.

2 roles · 1 guidelines · 0 courses · 0 providers

Relapse-prevention support

Help patients navigate craving, relapse risk, and post-treatment vulnerability. The manual notes that fear of relapse is more realistic than fear of withdrawal after ibogaine.

2 roles · 1 guidelines · 0 courses · 0 providers

Research-professional role separation

Distinguish psychotherapy/facilitation functions from outcome assessment and other research tasks. Separation reduces bias and protects the integrity of blinded assessments.

2 roles · 1 guidelines · 0 courses · 0 providers

Risk and contraindication screening

Facilitators must know the risks and contraindications associated with ayahuasca use. They should identify medical and psychological factors that make participation unsafe or require extra caution.

2 roles · 1 guidelines · 0 courses · 0 providers

Risk education and expectation setting

Can explain common, psychological, and severe risks of KAP in understandable terms. Sets realistic expectations that outcomes may vary and are not guaranteed.

2 roles · 1 guidelines · 0 courses · 0 providers

Risk management for vulnerable bereaved participants

Therapists must monitor a clinically vulnerable population experiencing recent loss and possible PGD risk. The protocol requires special attention to psychological destabilization, distress, and functional impairment.

2 roles · 1 guidelines · 0 courses · 0 providers

Route-specific administration awareness

Facilitators need working knowledge of administration routes because onset, duration, intensity, and tolerability vary substantially. This informs preparation, monitoring, and participant education.

2 roles · 1 guidelines · 0 courses · 0 providers

Safe physical intervention awareness

If physical intervention is needed, it must be done carefully to reduce risk such as choking or aspiration. The facilitator should understand safer alternatives and avoid dangerous techniques.

1 role · 1 guidelines · 0 courses · 0 providers

Safety and role-appropriateness judgment

Ability to recognize when a source does not provide enough information to infer clinical safety responsibilities or therapist competencies. This prevents unsupported claims about monitoring or intervention delivery.

1 role · 1 guidelines · 0 courses · 0 providers

Safety attunement

Maintain physical, emotional, and relational safety as the primary guiding principle throughout IMAP. Therapists continuously monitor risk, reinforce boundaries, and intervene more directly when safety is compromised.

1 role · 1 guidelines · 0 courses · 0 providers

Safety escalation and collaboration

Knows when to involve physicians, psychologists, and independent safety oversight. Complex psychedelic sessions require clear escalation pathways and team coordination.

1 role · 1 guidelines · 0 courses · 0 providers

Sedation and comfort management

Recognize when post-session exhaustion or discomfort may warrant supportive symptom management and understand the limited use of sedatives in the protocol. The facilitator must balance comfort with safety and document any sedating agents used.

1 role · 1 guidelines · 0 courses · 0 providers

Sedation judgment

Decide when sedation is appropriate and select agents that have been used safely in the manual’s reports. Sedation is presented as optional and patient-specific, not routine.

2 roles · 1 guidelines · 0 courses · 0 providers

Session format competence

Facilitators should understand how to work in one-on-one, group, and advanced simultaneous group formats. They must clearly explain the context, method, and risks of their chosen format.

2 roles · 1 guidelines · 0 courses · 0 providers

Session-day eligibility and compliance checks

Clinicians must ensure participants meet day-of-session safety requirements before psilocybin is administered. This includes verifying toxicology, pregnancy, alcohol abstinence, and adherence to protocol restrictions.

2 roles · 1 guidelines · 0 courses · 0 providers

Set shaping and mindset influence

The facilitator influences the participant’s mindset through tone, language, responsiveness, and overall presence. They should intentionally support a conducive mental set from first contact through post-session care.

1 role · 1 guidelines · 0 courses · 0 providers

Short-duration session management

The facilitator should be able to manage a brief but intense treatment window. The source suggests a shorter-acting psychedelic may enable rapid onset of response and reduce burden compared with longer-acting agents.

1 role · 1 guidelines · 0 courses · 0 providers

Social support assessment and guidance

Therapists must assess the participant’s social support network and help plan appropriate use of supportive relationships during treatment. They should guide participants about the potential benefits and risks of sharing their experiences with others.

1 role · 1 guidelines · 0 courses · 0 providers

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2 roles · 1 guidelines · 0 courses · 0 providers

Study design integrity

Supports rigorous conduct of randomized controlled safety studies by maintaining protocol adherence and minimizing bias. Protects the validity of safety, tolerability, and exploratory efficacy assessments.

2 roles · 1 guidelines · 0 courses · 0 providers

Substance composition and batch awareness

Know that ayahuasca composition can vary and that chemical characterization matters. Facilitators or clinical teams should understand the potency and stability of the administered brew.

2 roles · 1 guidelines · 0 courses · 0 providers

SUDS-guided exposure monitoring

Use Subjective Units of Distress Scale ratings to track fear activation and extinction during PE sessions. This requires eliciting reliable distress ratings and using them to guide exposure processing.

2 roles · 1 guidelines · 0 courses · 0 providers

Supervised at-home treatment oversight

Ability to support supervised at-home ketamine use when clinically appropriate. This implies monitoring and structure even outside the office setting.

1 role · 1 guidelines · 0 courses · 0 providers

Supportive context design

The article indicates that a structured, supportive context is associated with more positive acute and enduring effects and fewer challenging experiences. Facilitators should actively design the session context around safety and support.

2 roles · 1 guidelines · 0 courses · 0 providers

Supportive-expressive psychedelic psychotherapy

Therapists must be able to help participants confront, tolerate, and work through intense experiences rather than prematurely suppress them. The method emphasizes support, reassurance, emotional processing, and integration of meaningful material.

1 role · 1 guidelines · 0 courses · 0 providers

Therapeutic boundary and contingency planning

Respect patient autonomy while maintaining safety boundaries during a high-risk intervention. The protocol allowed return to opioid substitution therapy when clinically needed.

1 role · 1 guidelines · 0 courses · 0 providers

Track verbal and nonverbal cues

Therapists must closely attend to the patient's speech, affect, movement, silence, and bodily signs to understand process and determine appropriate intervention. Fine-grained observation is necessary for both safety and therapeutic timing.

1 role · 1 guidelines · 0 courses · 0 providers

Training and supervision compliance

Operate only within the bounds of formal training, supervision, and site authorization. The protocol expects specialized training for facilitators, raters, and all staff interacting with participants or data.

3 roles · 1 guidelines · 0 courses · 0 providers

Trauma-informed, non-threatening interviewing

Use a caring, natural, and non-threatening interview style to assess psychiatric and psychological domains. The protocol emphasizes normalization, reduction of guilt, symptom exaggeration techniques, and a logical flow that facilitates rapport.

2 roles · 1 guidelines · 0 courses · 0 providers

Understanding of bipolar-specific risk context

The facilitator must understand why bipolar II participants require enhanced monitoring and conservative dosing. The protocol is built around the risk of mood destabilization in this population.

1 role · 1 guidelines · 0 courses · 0 providers

Understanding of dose-response limitations

Recognize that current evidence does not establish the lowest effective or safest exposure for ibogaine. Facilitators must understand the uncertainty surrounding efficacy at reduced doses.

1 role · 1 guidelines · 0 courses · 0 providers

Understanding of grief and PGD

Facilitators need conceptual knowledge of normal grief, prolonged grief disorder, and the rationale for preventive and therapeutic grief care. This informs formulation, pacing, and risk awareness in the protocol.

1 role · 1 guidelines · 0 courses · 0 providers

Understanding of study schedule and visit procedures

Facilitators must know the study timeline to conduct therapy and safety checks at the correct times. They should understand which visits are in person, virtual, or questionnaire-only and what assessments occur at each stage.

1 role · 1 guidelines · 0 courses · 0 providers

Use and training of overnight attendants

Facilitators must coordinate appropriate overnight support personnel and ensure they are trained for the role. Attention to participant comfort and boundaries is built into staffing decisions.

2 roles · 1 guidelines · 0 courses · 0 providers

Use of cognitive and behavioral assessment domains

Understand the domains assessed in the Storyline psychiatric and neurological interviews and use this knowledge to support accurate administration and interpretation of study tasks. Domains include cognition, mood, homeostasis, social support, and psychosis/suicidality screening.

2 roles · 1 guidelines · 0 courses · 0 providers

Validate affirming experiences as healing

Therapists should validate positive, affirming, and resourcing experiences as meaningful components of healing, growth, and meaning-making.

1 role · 1 guidelines · 0 courses · 0 providers

Vital sign and clinical observation awareness

Understand the expected acute physiological effects of BPL-003 and monitor for clinically meaningful changes. The facilitator should recognize that transient blood pressure and heart rate increases may occur.

1 role · 1 guidelines · 0 courses · 0 providers

Withdrawal and craving support

Monitor and address nicotine withdrawal symptoms and smoking urges across the treatment window. Facilitators help participants manage discomfort and sustain abstinence through high-risk periods.

2 roles · 1 guidelines · 0 courses · 0 providers

Work collaboratively in therapist dyads and supervised teams

Psilocybin sessions are conducted with two trained therapists, and therapists-in-training may support sessions under supervision. Effective dyad work and supervised learning are central to the model.

2 roles · 1 guidelines · 0 courses · 0 providers

Case-based practice, peer consultation, and professional learning community

Teaches applied competence through role play, case discussion, peer consultation, seminars, mentorship, and learning-community structures. The emphasis is translating theory into practice, receiving feedback, and developing reflective clinical judgment with peers.

7 roles · 0 guidelines · 8 courses · 7 providers

Ethics and ethical practice

Cluster covering 4 related competencies including: Ethical practice, Ethics in psychedelic care, Ethics and ethical practice.

6 roles · 0 guidelines · 4 courses · 3 providers

Preparation and therapeutic alliance

Cluster covering 2 related competencies including: Preparation and therapeutic alliance, Preparation and therapeutic alliance building.

3 roles · 0 guidelines · 2 courses · 2 providers

Psilocybin prescribing fundamentals

Cluster covering 2 related competencies including: Psilocybin prescribing fundamentals, Prescribing fundamentals for psychedelic treatment.

2 roles · 0 guidelines · 2 courses · 1 providers

Clinical documentation and coordination

Some listed programs explicitly teach clinical documentation and related practice management skills. This suggests learners may be expected to document care, coordinate treatment processes, and work within structured clinical workflows.

3 roles · 0 guidelines · 1 courses · 1 providers

Clinical trial training and feedback use

The page highlights best-in-class clinical training for drug trials and AI-supported evaluation. Learners are expected to refine skills quickly and receive targeted feedback in training or evaluation contexts.

6 roles · 0 guidelines · 1 courses · 1 providers

Contraindication and interaction review

The page explicitly notes medication interactions, contraindications, and risk management for prescribers. This indicates training in identifying unsafe combinations and excluding or delaying treatment when needed.

2 roles · 0 guidelines · 1 courses · 1 providers

Ethical decision-making and confidentiality

The practicum explicitly says sites cover ethical considerations such as confidentiality, privacy, professional conduct, and ethical decision-making. Ethical alignment is also part of site approval.

7 roles · 0 guidelines · 1 courses · 1 providers

Ethical grounding and integrity

The course repeatedly emphasizes ethical considerations, safety, and integrity in practice. Learners are expected to develop a grounded professional stance that respects legal boundaries and participant welfare.

6 roles · 0 guidelines · 1 courses · 1 providers

Respond ethically and relationally in crisis

The course explicitly includes ethical and relational considerations in crisis response. This suggests learners are trained to act with care, boundaries, and attunement when responding to acute distress.

4 roles · 0 guidelines · 1 courses · 1 providers

Safety and legal boundaries awareness

The page includes explicit warnings about what graduates can and cannot legally do. Learners are expected to understand scope limits, licensure requirements, and when consultation supervision is needed.

5 roles · 0 guidelines · 1 courses · 1 providers

Safety-oriented documentation and templates

Trainees receive templates such as consent and intake forms, informational documents, and guidelines, which implies competence in using standardized practice materials. The page also signals procedural support for safe and organized care delivery.

5 roles · 0 guidelines · 1 courses · 1 providers

Safety, ethics, and responsibility in expanded states work

The course explicitly states that facilitators are guided in safety, ethics, and responsibility. Learners are expected to recognize and manage the unique risks of working with altered states.

3 roles · 0 guidelines · 1 courses · 1 providers

Working within legal and approved site structures

The practicum requires placements at pre-approved sites and emphasizes legal and ethical standards. Learners are exposed to different settings, including clinical, retreat, and harm reduction organizations.

4 roles · 0 guidelines · 1 courses · 1 providers

Virtual safety and support management

The program states that the virtual training has been streamlined so students feel safe and supported no matter what arises. This signals competency in maintaining safety in online psychedelic support contexts.

3 roles · 0 guidelines · 0 courses · 1 providers

General psychedelic-assisted practice skills

Catch-all cluster covering 189 general competencies for psychedelic-assisted clinical practice that did not group into a more specific category — including miscellaneous facilitation, monitoring, ethics, safety, regulatory awareness, group support, and program-specific skills not captured by dedicated clusters elsewhere.

8 roles · 45 guidelines · 27 courses · 18 providers