Luiz Tófoli

Luiz F. Tófoli is a Brazil-based clinical researcher whose work bridges empirical, qualitative and psychometric approaches within contemporary psychedelic science. Tófoli has contributed to large-scale survey research (including analyses from the Global Ayahuasca Survey) that characterises adverse events, use patterns and wellbeing outcomes among ayahuasca users, and has led or co-authored studies examining subjective experiential reports through quantitative textual and phenomenological methods. He has also investigated the influence of context and setting on ayahuasca outcomes and contributed to the development and review of psychometric instruments for psychedelic research.

In addition to naturalistic and survey work, Tófoli has been involved in clinical and treatment-focused research, including an open-label pilot of MDMA-assisted psychotherapy for victims of sexual abuse with severe PTSD and phenomenological analyses of ibogaine in the context of drug-dependence treatment. His publications emphasise safety profiles, subjective experience, and methodological rigour for studying both therapeutic potential and risks of classic and non-classic psychedelics, with recurrent focus on depressive disorders, PTSD and substance-use disorders.