Patrick Dolder

Patrick C. Dolder is a clinical psychopharmacology researcher known for conducting rigorous, placebo‑controlled experimental studies in healthy volunteers to map the acute effects and pharmacokinetics of lysergic acid diethylamide (LSD) and related psychoactive drugs. He has frequently collaborated with established psychopharmacology groups in Switzerland and Europe, contributing to work that uses double‑blind designs, pharmacokinetic sampling, psychometric assessment and neuroimaging to examine dose–response relationships and safety profiles.

Dolder's publications span dose‑dependent characterisations of LSD, investigations of low (micro) doses and their behavioural and subjective effects, and studies probing biological correlates such as circulating steroid levels and response‑inhibition neural networks. He has also contributed to comparative studies of stimulants and entactogens on emotion processing and to observational research on self‑reported microdosing. His work has informed clinical and basic understanding of acute psychedelic effects, methodological standards for human experimental paradigms, and the emerging dialogue on microdosing and therapeutic potential while emphasising careful pharmacological characterisation and safety monitoring.