Dominik Dornbierer

Clinical Pharmacologist

Data updated

Papers

10 publications

Trials

0 clinical trials

Research Footprint

Dominik Dornbierer appears in 10 tracked papers (2023–2025), most studied alongside Ayahuasca, DMT and Placebo, across Healthy Volunteers, Depressive Disorders and Medicinal Chemistry & Drug Development.

Most-cited paper: Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects (31 citations).

Frequent co-authors: Milan Scheidegger, Anne Aicher and Helena Aicher.

Background & Research

Dominik A. Dornbierer is a clinical pharmacologist and researcher focused on the acute human pharmacology of psychedelic tryptamines and beta‑carbolines. His recent work centres on ayahuasca‑inspired formulations combining N,N‑dimethyltryptamine (DMT) with harmine, investigating dose–response relationships, pharmacokinetic–pharmacodynamic interactions and population PK‑PD modelling in healthy volunteer cohorts. Dornbierer has been involved in randomised controlled studies examining psychological outcomes such as mindfulness and compassion, experimental paradigms probing creativity during artistic creation, and neuroimaging work exploring self–other face differentiation under DMT/harmine influence.

He brings methodological expertise in factorial dose‑escalation designs, population pharmacokinetic and pharmacodynamic modelling, and multimodal outcome assessment (behavioural, psychometric and neuroimaging). Dornbierer’s contributions aim to characterise safety, acute subjective effects and mechanistic markers that can inform dose selection and translational development of serotoninergic psychedelic compounds for psychiatric research.

Affiliations

Institutions, companies, and organisations Dominik Dornbierer is associated with.