Revista de Psiquiatría y Salud Mental

Efficacy and safety of ketamine in bipolar depression: A systematic review

This review (2017) compared the safety and efficacy of ketamine for bipolar depression across scientific studies (1 clinical trial, 4 case studies, 5 cohort studies), which showed that symptoms are reduced swiftly and effectively in response to treatment, but they reappear relatively quickly within 3-14 days depending on the scale used to measure symptoms. Ketamine may be considered safe and effective for treating some cases of bipolar depression, although it has a short duration of action, in the absence of confirming studies designed specifically for bipolar depression.

Published

April 1, 2017

Journal

Revista de Psiquiatría y Salud Mental

Authors

Alberich, S., Martínez-Cengotitabengoa, M., López, P., Zorrilla, I., Nuñez, N. A., Vieta, E., González-Pinto, A.