Metabolic Engineering

In vivo production of psilocybin in E. coli

This synthesis article (2019) explains the gram-scale production of psilocybin in E. coli (a prokaryotic host), which is a 32-fold improvement over earlier techniques. However, it's still much more expensive than growing it in mushrooms/truffles.

Published

December 1, 2019

Journal

Metabolic Engineering

Authors

Adams, A. M., Kaplan, N. A., Wei, Z., Brinton, J. D., Monnier, C. S., Enacopol, A. L., Ramelot, T. A., Jones, J. A.