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Academic Journal

Journal of Medicinal Chemistry

2 Papers Indexed in Blossom

Data updated

Research Footprint

Journal of Medicinal Chemistry has 2 tracked papers indexed in Blossom (2014–2021) from 17 authors, most often covering 2C-X and Salvia Divinorum, across Medicinal Chemistry & Drug Development, Autism Spectrum Disorder (ASD) and Depressive Disorders.

Published Papers

Open Accessindividual

Discovery of G Protein-Biased Antagonists against 5-HT7R

This mouse study explored the effects of a number of synthetic psychoactive drugs, such as the 2C-family, on the serotonin receptor 5-HT7R. The ability of a particular 2C compound to bind 5-HT7R over other subtypes and reduce self-grooming time in mice suggests that 5-HT7R could be a potential target for treating autism.

Published
Journal
Journal of Medicinal Chemistry
Authors
Lee, H., Lee, J., Kim, D., Kim, H., Kim, J., Yeom, M., Cho, Y., Keum, G., Jeon, B., Choo, H., Kwang, R.
Paywallindividual

Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues

This animal study (n=12) synthesized several different furan-substituted salvinorin A analogs and identified three potent variants which reduced drug-induced reinstatement of cocaine-seeking behavior, without producing the sedation observed with other κ-opioid agonists.

Published
Journal
Journal of Medicinal Chemistry
Authors
Riley, A. P., Groer, C. E., Young, D., Ewald, A. W., Kivell, B. M., Prisinzano, T. E.

Quick Facts

Papers Indexed
2
h-Index
314
Open Access
No
Publisher
American Chemical Society
Country
United States
Website
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