Archives of Gynecology and Obstetrics

Single bolus low-dose of ketamine does not prevent postpartum depression: a randomized, double-blind, placebo-controlled, prospective clinical trial

This randomised-controlled trial (n=330) assessed the efficacy of low-dose ketamine (17.5mg/70kg diluted to 10 mL with 0.9% saline) administered during caesarean section in preventing postpartum depression (PPD). No significant differences were found in the prevalence of PPD between the active group and the placebo group at 3 days and 6 weeks after delivery. Pain scores were significantly different at 6 weeks only.

Published

March 29, 2017

Journal

Archives of Gynecology and Obstetrics

Authors

Yang, X., Yuantao, L., Xialei, H., Daili, C., Baozuan, S., Daqing, M.