This course provides an overview of MDMA as a potential treatment for post-traumatic stress disorder (PTSD). It traces MDMA’s history from early psychiatric use to recreational adoption and renewed clinical interest. The content focuses on the current research landscape, including work led by MAPS and findings on safety and efficacy when MDMA is used under professional guidance in controlled settings. It also reviews important safety considerations and contraindications discussed in the source material. The course is relevant for clinicians, therapists, and other mental health professionals interested in emerging PTSD treatments and the evidence supporting MDMA-assisted therapy.