MDMA-Assisted Therapy Open Clinical Series: Subjective Reports (Greer & Tolbert, San Francisco / Santa Fe 1980–1983)
This unregistered trial (n=29) was an uncontrolled clinical observational series of MDMA-assisted sessions for various therapeutic goals in self-referred participants, focusing primarily on the subjective and phenomenological reports of the experience.
Detailed Description
This synthetic trial has been added to our database because a psychedelic paper (about a clinical trial) references this trial, but no (live) registration can be found. The study was an open, uncontrolled observational series conducted between 1980 and 1983 in California and New Mexico. The researchers collected phenomenological descriptions of the therapists' observations and the subjects' experiences before, during, and after the MDMA sessions.
The intervention involved the oral administration of MDMA, with some participants receiving a second dose to extend the duration of the session. Because the primary objective was to assist participants in achieving their individual therapeutic goals, the study did not include placebo controls, double-blind assessments, or formal psychological evaluations by independent observers.
Study Arms & Interventions
MDMA
experimentalOral administration of MDMA, with some subjects receiving a second dose to prolong the session.
Interventions
- MDMA25 mgvia Oral• single dose• 1 doses total
Initial oral dose ranged from 25-150 mg. Some subjects received a second dose of 50 mg or 75 mg to prolong the session.
Study Details
- StatusCompleted
- Typeinterventional
- DesignNon-randomized
- Target Enrollment29 participants
- TimelineStart: 1980-01-01End: 1983-12-31
- Compound
- Topic