National Network of Depression Centers

The National Network of Depression Centers is a U.S.-based nonprofit consortium of academic medical centers and mental health programs focused on depression, bipolar disorder, and related mood disorders. It operates nationally across member sites in the United States and is centered in Ann Arbor, Michigan. Its core activities include collaborative research, clinical education, outreach, and network-based improvement of evidence-based care.

In the psychedelic-adjacent space, NNDC appears primarily as a mood-disorders research and clinical collaboration network rather than a dedicated psychedelic policy group. Its ketamine task group was created to share information and experience as ketamine and esketamine clinics expanded across the network, and NNDC has also reported on the BIO-K biomarker study of ketamine for major depression. This makes it relevant to researchers, clinicians, and funders working on interventional psychiatry, treatment-resistant depression, and evidence-building around regulated access pathways.