Massachusetts General Hospital

The Center for the Neuroscience of Psychedelics aims to better understand how psychedelics can be used to improve the treatment of mental illnesses. The core mission of the center is to understand exactly how psychedelics enhance the brain's capacity for change—or neuroplasticity—to optimize current treatments and render the term treatment resistant obsolete.

Massachusetts General Hospital

Academic Research

Recent Papers

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Sponsored Trials

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Treatment Resistant MDD

N-methyl-D-aspartate Antagonist (Ketamine) Augmentation of Electroconvulsive Treatment for Severe Major Depression

A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)

The Impact of Ketamine on the Reward Circuitry of Suicidal Patients

Physiological and Cognitive Biomarkers for Ketamine’s Antidepressant Effects

Ketamine for Depression: An MRI Study

Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder

Intranasal Ketamine for Late-Life Depression and Suicidal Ideation

Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)

Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

Collaborated Trials

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan (REaKT-SD)

Ketamine Treatment of Youth Suicide Attempters

Psilocybin for Psychological and Existential Distress in Palliative Care

Sequential Therapy for the Treatment of Severe Bipolar Depression

Research Papers

Trip sitting or just sitting? Session facilitators substantially influence psychedelic experiences in clinical trials but not in healthy ones

Events

3rd Annual Conference on Psychedelics and Psychedelic Medicine

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