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Lead program: Preclinical
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Journey Colab

Data updated

1 Drug Candidate

Journey Colab is a US psychedelic pharmaceutical company developing synthetic mescaline hydrochloride for alcohol use disorder (AUD). Founded in 2020, the company has raised $30.7M from investors including Sam Altman, Apollo Projects, and Drew Houston. Journey Colab has dedicated 10% of its founding equity to a Reciprocity Trust supporting Indigenous communities from which mescaline knowledge originates. The company is partnering with All Points North (APN) for an FDA-authorised Phase 2 clinical trial.

Pipeline Intelligence

Developer Momentum

Programme tracker
Active candidates
1

All tracked candidates active

Active programmes
1

All tracked programmes active

Lead stage
Preclinical

Current furthest stage

Forecast coverage
1 of 1

1 active programme with forecast fields

Latest sourced update

Mescaline HCl - Journey Colab

Jun 26, 2026 - drug-database - AdisInsight - JOUR-5700 (Synthetic Mescaline HCl)

Next known catalyst

Phase I started

Timing not specified - JOUR-5700 (Synthetic Mescaline HCl) / JOUR-5700 Programme (AUD) — Pre-Phase 1 - Confidence: 30%

5 sources0 pipeline-linked trials0 pipeline-linked papers

Development Programmes

1

JOUR-5700 (Synthetic Mescaline HCl)

Mescaline
Preclinical

Alcohol use disorder

Programme Tracker

Alcohol Use Disorder (AUD)

Primary: US (FDA)
Pre-clinicalActive

Forecast

Phase I started

JOUR-5700 remains a preclinical mescaline HCl AUD programme in public databases and historical company coverage; no ClinicalTrials.gov registration or recent Journey Colab clinical-start update was found in this pass.

Milestones

Funding milestone

Completed

Actual: Jan 1, 2020

Founded by Dr Jeeshan Chowdhury and Jennifer Pisansky; $3M seed from Apollo Projects (Sam Altman's moonshot fund)

Why it matters: First company to pursue synthetic mescaline through FDA clinical development. Apollo Projects backing (Sam Altman) signals Silicon Valley interest in psychedelic medicine for addiction.

Funding milestone

Completed

Actual: Oct 1, 2022

$12M Series A raised (total $15M); preclinical and CMC programmes completed

Why it matters: Well-capitalized for Phase 1 entry. Preclinical and chemistry/manufacturing/controls completion means JOUR-5700 is Phase 1-ready from a drug development perspective.

Company milestone

Completed

Actual: Oct 1, 2022

Nature profile published on mescaline clinical development and Journey Colab's approach

Why it matters: Nature coverage validates the scientific rationale for mescaline in AUD. Mescaline is the only classical psychedelic with no modern clinical trial data — it was studied extensively in the 1950s-60s for alcoholism but never progressed through modern regulatory frameworks.

Company milestone

Completed

Actual: Dec 1, 2023

Last known public activity — no press releases, no NCT registered, no trial recruitment announced since late 2023

Why it matters: Phase 1 at CHDR was expected to begin by 2023 but appears not to have started. Over 2 years of silence is concerning. Company is still listed as active on PitchBook/Crunchbase with $15M total raised. May be in stealth-mode development or facing funding/regulatory challenges.

Watch next: Phase 1 trial registration on ClinicalTrials.gov; CHDR site activation; any press release or funding announcement

Recorded Events

Dec 1, 2023: Company milestone

Oct 1, 2022: Funding milestone

Oct 1, 2022: Company milestone

Jan 1, 2020: Funding milestone

Evidence Links

Mescaline HCl - Journey Colab

drug-database - AdisInsight - Jun 26, 2026 - Verified

Drug profile identifies JOUR-5700 synthetic mescaline HCl as Journey Colab preclinical AUD candidate.

Journey Colab Scores 12M to Move Addiction Treatment Toward Clinic

industry-media - Fierce Biotech - Sep 7, 2021 - Verified

Series A coverage describes Journey Colab plan to move a mescaline-based AUD programme toward first human testing.

From Cultural Rite to Clinical Trial - Mescaline Potential

industry-media - QPS - Nov 28, 2022 - Verified

QPS article describes JOUR-5700 as synthetic mescaline being developed for AUD and planned ascending-dose study.

Similar Developers

Reference points selected from shared pipeline stage, indications, compounds, regulatory pathways, and evidence footprint.

View landscape
Kuleon Bioscience
Preclinical1 active candidate
same indication: Alcohol Use Disorder (AUD)Preclinical peersame regulator: US FDAsimilar active pipeline size
Tactogen
Preclinical2 active candidates
same indication: Alcohol Use Disorder (AUD)Preclinical peersame regulator: US FDAsimilar active pipeline size
Psilera
Preclinical3 active candidates1 paper
same indication: Alcohol Use Disorder (AUD)Preclinical peersame regulator: US FDAboth have forecast coverage
Biomind Labs
Phase II2 active candidates3 trials
shared compound: Mescalinesame regulator: US FDAsimilar active pipeline sizeboth have forecast coverage

Quick Facts

Type
Private Biotech
Founded
2020
Lead Stage
Preclinical
Website
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