Serotonin and stress coping

This review connects serotonin signaling to stress coping, especially how different serotonin pathways shape active or passive responses to aversive situations. It matters here because receptor theories of psychedelics often draw on the same stress-coping framework used to compare 5-HT1A and 5-HT2A function.

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Authors

  • Puglisi-Allegra, S.
  • Andolina, D.

Published

Behavioural Brain Research
meta Study
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Research Summary of 'Serotonin and stress coping'

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βBlossom's Take

This review is useful because it places serotonin within a stress-coping framework that also informs how 5-HT1A and 5-HT2A signalling are often discussed in psychedelic research. Its value is conceptual rather than directly psychedelic, but it helps separate active from passive coping in a way that is relevant to interpreting serotonergic drug effects.

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