World Medical & Health Policy

The Potential Economic and Public Health Impact of MDMA-Assisted Group Therapy for PTSD in Ukraine

Using a decision-analysis model for 1,000 Ukrainian PTSD patients, the study estimates MDMA-assisted group therapy with supplemental individual sessions would cost US$1.1m, avert 19.2 deaths, gain 717 QALYs, have an ICER of US$1,537/QALY and produce net societal savings of US$2.6m, with scaled 50% coverage over 10 years potentially saving ~48,000 lives, 1.5 million QALYs and US$5.6bn. These results indicate MAT is likely to be cost‑effective or cost‑saving and could substantially improve population health, supporting its inclusion in Ukraine’s PTSD treatment strategy.

Published

August 21, 2025

Journal

World Medical & Health Policy

Authors

Marseille, E., Chernoloz, O., Orlov, |. O.