Psychoneuroendocrinology

Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans

This double-blind trial (n=14) compared the effects of MDMA (52.5-105 mg/70kg), intranasal oxytocin (20 IU or 40 IU), and placebo on plasma oxytocin concentrations. MDMA (105 mg/70kg only) increased plasma oxytocin levels to a mean peak of 83.7 pg/ml at approximately 90-120 min compared to a 48.0 pg/ml, 30-60 min increase after oxytocin administration.

Published

August 1, 2014

Journal

Psychoneuroendocrinology

Authors

Kirkpatrick, M. G., Francis, S. M., Lee, R., de Wit, H., Jacob, S.