Phytotherapy Research

The effect of Banisteriopsis caapi (B. caapi) on the motor deficits in the MPTP-treated common marmoset model of Parkinson’s disease

This animal study (n=8) investigated the efficacy of Banisteriopsis caapi (0.1 -; 0.3 mg/kg harmine) alone and in combination with L-DOPA (4 -; 7 mg/kg) to treat parkinsonian dyskinesia in a marmoset disease model. B. caapi alone has a mild antiparkinsonian effect but does not enhance the L-DOPA response or reduce dyskinesia.

Published

January 24, 2018

Journal

Phytotherapy Research

Authors

Fisher, R., Lincoln, L., Jackson, M. J., Abbate, V., Jenner, |. P., Hider, R., Lees, |. A., Rose, S.