npj Aging

Psilocybin treatment extends cellular lifespan and improves survival of aged mice

This mouse study (n=58) provides the first experimental evidence that psilocin extends cellular lifespan and that psilocybin promotes increased longevity in aged mice. The findings suggest psilocybin may have geroprotective potential, though the molecular mechanisms remain unclear.

Published

July 8, 2025

Journal

npj Aging

Authors

Kato, K., Kleinhenz, J. M., Shin, Y. J., Coarfa, C., Zarrabi, A. J., Hecker, L.