Clinical competency
Awareness of functional unblinding
Recognize that strong psychoactive effects can reveal treatment allocation and influence ratings. This awareness is important for interpreting subjective reports and maintaining methodological rigor.
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Linked guidelines (1)
Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine benzoate) in healthy participants
5-MeO-DMTEvidence score: 90
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